4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide

Modify Date: 2024-01-08 19:05:45

4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide Structure
4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide structure
Common Name 4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide
CAS Number 1027345-11-4 Molecular Weight 567.62200
Density N/A Boiling Point N/A
Molecular Formula C21H24F3N3O6S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-[[(2R)-4-morpholin-4-yl-4-oxo-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)benzenesulfonamide

 Chemical & Physical Properties

Molecular Formula C21H24F3N3O6S3
Molecular Weight 567.62200
Exact Mass 567.07800
PSA 177.93000
LogP 5.32200

 Synthetic Route

~86%

4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide Structure

4-[[(1R)-3-(4-M...

CAS#:1027345-11-4

Literature: ASTRAZENECA AB Patent: US2012/35134 A1, 2012 ; Location in patent: Page/Page column 55; 56 ;

~77%

4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide Structure

4-[[(1R)-3-(4-M...

CAS#:1027345-11-4

Literature: GENENTECH, INC.; WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH Patent: WO2008/61208 A2, 2008 ; Location in patent: Page/Page column 38 ; WO 2008/061208 A2

~%

4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide Structure

4-[[(1R)-3-(4-M...

CAS#:1027345-11-4

Literature: US2012/35134 A1, ;

~%

4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide Structure

4-[[(1R)-3-(4-M...

CAS#:1027345-11-4

Literature: US2012/35134 A1, ;

~%

4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide Structure

4-[[(1R)-3-(4-M...

CAS#:1027345-11-4

Literature: US2012/35134 A1, ;

~%

4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide Structure

4-[[(1R)-3-(4-M...

CAS#:1027345-11-4

Literature: US2012/35134 A1, ;

~%

4-[[(1R)-3-(4-Morpholinyl)-3-oxo-1-[(phenylthio)methyl]propyl]amino]-3-trifluoromethylsulfonyl-benzenesulfonamide Structure

4-[[(1R)-3-(4-M...

CAS#:1027345-11-4

Literature: US2012/35134 A1, ;