Tos-PEG7-OH

Modify Date: 2024-01-10 18:46:53

Tos-PEG7-OH Structure
Tos-PEG7-OH structure
Common Name Tos-PEG7-OH
CAS Number 1028089-05-5 Molecular Weight 480.569
Density 1.2±0.1 g/cm3 Boiling Point 554.5±50.0 °C at 760 mmHg
Molecular Formula C21H36O10S Melting Point N/A
MSDS N/A Flash Point 289.1±30.1 °C

 Use of Tos-PEG7-OH


Tos-PEG7-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PEG8-Tos
Synonym More Synonyms

 Tos-PEG7-OH Biological Activity

Description Tos-PEG7-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 554.5±50.0 °C at 760 mmHg
Molecular Formula C21H36O10S
Molecular Weight 480.569
Flash Point 289.1±30.1 °C
Exact Mass 480.202911
LogP -1.30
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.488

 Synonyms

MFCD24539472
2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, benzenesulfonate
2,5,8,11,14,17,20-Heptaoxadocosan-22-yl benzenesulfonate