Intermedine
Intermedine structure
|
Common Name | Intermedine | ||
|---|---|---|---|---|
| CAS Number | 10285-06-0 | Molecular Weight | 299.36300 | |
| Density | 1.26g/cm3 | Boiling Point | 463.3ºC at 760mmHg | |
| Molecular Formula | C15H25NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 234ºC | |
Use of Intermedine(+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxicity in neural progenitor cells (NPCs)[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | intermedine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | (+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxicity in neural progenitor cells (NPCs)[1]. |
|---|---|
| Related Catalog | |
| In Vitro | (+)-Intermedine (1.1-30 μM; 24 hours) exhibits significant cytotoxicity at 30 μM and reduces cell viability in a concentration dependent manner in neural progenitor cells (NPCs)[1]. (+)-Intermedine showsno differentiation impairment[1]. Cell Cytotoxicity Assay[1] Cell Line: Neural progenitor cells (NPCs) Concentration: 1.1, 3.3, 10, 30 μM Incubation Time: 24 hours Result: Exhibited significant cytotoxicity at 30 μM and reduced cell viability in a concentration dependent manner. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.26g/cm3 |
|---|---|
| Boiling Point | 463.3ºC at 760mmHg |
| Molecular Formula | C15H25NO5 |
| Molecular Weight | 299.36300 |
| Flash Point | 234ºC |
| Exact Mass | 299.17300 |
| PSA | 90.23000 |
| Vapour Pressure | 1.57E-10mmHg at 25°C |
| Index of Refraction | 1.567 |
| InChIKey | SFVVQRJOGUKCEG-OPQSFPLASA-N |
| SMILES | CC(C)C(O)(C(=O)OCC1=CCN2CCC(O)C12)C(C)O |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| RIDADR | UN 1544 |
|---|---|
| Packaging Group | III |
| Hazard Class | 6.1(b) |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| [(7R,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2S)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate |
| Intermedina [INN-Spanish] |
| Butanoic acid,2,3-dihydroxy-2-(1-methylethyl)-,((1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester,(2S,3R) |
| 9-(+)-Trachelanthylretronecine |
| lycopsamine |
| Intermedine |
| Intermedinum [INN-Latin] |
| [(1r,7ar)-1-hydroxy-2,3,5,7a-tetrahydro-1h-pyrrolizin-7-yl]methyl(2s,3r)-2,3-dihydroxy-2-(propan-2-yl)butanoate |
| Intermedina |
| Intermedinum |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the SMILES notation of intermedine? |
| A: SMILES notation of intermedine is CC(C)C(O)(C(=O)OCC1=CCN2CCC(O)C12)C(C)O. |
| Q: What is the English name of intermedine? |
| A: The English name of intermedine is intermedine. |
| Q: What is the boiling point of intermedine? |
| A: Boiling point of intermedine is 463.3ºC at 760mmHg. |
| Q: What is the InChIKey of intermedine? |
| A: InChIKey of intermedine is SFVVQRJOGUKCEG-OPQSFPLASA-N. |
| Q: What are the uses of intermedine? |
| A: Main uses of intermedine: (+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxicity in neural progenitor cells (NPCs)[1]. |
| Q: What is the polar surface area (PSA) of intermedine? |
| A: Polar surface area (PSA) of intermedine is 90.23000. |
| Q: What is the molecular formula of intermedine? |
| A: Molecular formula of intermedine is C15H25NO5. |
| Q: What is the CAS number of intermedine? |
| A: CAS number of intermedine is 10285-06-0. |
| Q: What is the molecular weight of intermedine? |
| A: Molecular weight of intermedine is 299.36300. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |