4-Chloro-3-nitroanisole

Modify Date: 2024-01-02 12:38:39

4-Chloro-3-nitroanisole Structure
4-Chloro-3-nitroanisole structure
Common Name 4-Chloro-3-nitroanisole
CAS Number 10298-80-3 Molecular Weight 187.580
Density 1.4±0.1 g/cm3 Boiling Point 293.3±20.0 °C at 760 mmHg
Molecular Formula C7H6ClNO3 Melting Point 41-43 °C(lit.)
MSDS Chinese USA Flash Point 131.2±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Chloro-3-nitroanisole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 293.3±20.0 °C at 760 mmHg
Melting Point 41-43 °C(lit.)
Molecular Formula C7H6ClNO3
Molecular Weight 187.580
Flash Point 131.2±21.8 °C
Exact Mass 187.003616
PSA 55.05000
LogP 2.65
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.560

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BZ8580000
CHEMICAL NAME :
Anisole, 4-chloro-3-nitro-
CAS REGISTRY NUMBER :
10298-80-3
BEILSTEIN REFERENCE NO. :
0640872
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H6-Cl-N-O3
MOLECULAR WEIGHT :
187.59
WISWESSER LINE NOTATION :
WNR BG EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04759

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS BZ8580000
HS Code 29093090

 Synthetic Route

~67%

4-Chloro-3-nitroanisole Structure

4-Chloro-3-nitr...

CAS#:10298-80-3

Literature: Moon, Mi Eun; Choi, Younghwa; Lee, Young Min; Vajpayee, Vaishali; Trusova, Marina; Filimonov, Victor D.; Chi, Ki-Whan Tetrahedron Letters, 2010 , vol. 51, # 51 p. 6769 - 6771

~31%

4-Chloro-3-nitroanisole Structure

4-Chloro-3-nitr...

CAS#:10298-80-3

Literature: Narender; Mohan, K.V.V. Krishna; Srinivasu; Kulkarni; Raghavan Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 6 p. 1335 - 1338

~%

4-Chloro-3-nitroanisole Structure

4-Chloro-3-nitr...

CAS#:10298-80-3

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2> 127, p. 20,22

~%

Detail
Literature: Australian Journal of Chemistry, , vol. 36, # 5 p. 1031 - 1035

 Customs

HS Code 2909309090
Summary 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles1

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Synthesis and antiinflammatory activity of 7-methanesulfonylamino-6-phenoxychromones. Antiarthritic effect of the 3-formylamino compound (T-614) in chronic inflammatory disease models.

Chem. Pharm. Bull. 48(1) , 131-9, (2000)

A group of derivatives of 7-methanesulfonylamino-6-phenoxychromone (1) at the pyrone and phenoxy rings was synthesized starting with 4-chloro-3-nitroanisole and evaluated against acute and chronic inf...

 Synonyms

4-chloro-3-nitrophenyl methyl ether
2-Chloro-5-Methoxynitrobenzene
1-Chloro-2-nitro-4-methoxybenzene
4-Chloro-3-nitroanisole
dioxoaMine
1-Chloro-4-methoxy-2-nitrobenzene
EINECS 233-674-1
4-methoxy-2-nitrochlorobenzene
2-fluoronitrobenzene
4-Chlor-3-nitro-anisol
MFCD00007077
3-NITRO-4-CHLOROANISOLE
4-chloro-3-nitro-anisol
2-Nitro-4-methoxychlorobenzene
Benzene, 1-chloro-4-methoxy-2-nitro-
4-chloro-3-nitro-anisole