L 888607 Racemate

Modify Date: 2025-08-25 16:39:42

L 888607 Racemate Structure
L 888607 Racemate structure
Common Name L 888607 Racemate
CAS Number 1030017-51-6 Molecular Weight 375.84400
Density N/A Boiling Point N/A
Molecular Formula C19H15ClFNO2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L 888607 Racemate


L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively.

 Names

Name 2-[4-(4-chlorophenyl)sulfanyl-7-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-3-yl]acetic acid
Synonym More Synonyms

 L 888607 Racemate Biological Activity

Description L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively.
Related Catalog
Target

DP/DP1:132 nM (Ki)

TP:17 nM (Ki)

In Vitro L 888607 Racemate (compound 3) maintains a modest binding affinity for the DP1 receptor (Ki = 132 nM) and is actually 8-fold more potent on the TP receptor (Ki = 17 nM)[1].
References

[1]. Beaulieu C, et al. Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2696-700.

 Chemical & Physical Properties

Molecular Formula C19H15ClFNO2S
Molecular Weight 375.84400
Exact Mass 375.05000
PSA 67.53000
LogP 5.54700
Storage condition 2-8℃

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

l-888,291
l-883,595
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