GUANOSINE 5'-DIPHOSPHATE TRIS SALT

Modify Date: 2024-02-11 09:19:33

GUANOSINE 5'-DIPHOSPHATE TRIS SALT Structure
GUANOSINE 5'-DIPHOSPHATE TRIS SALT structure
Common Name GUANOSINE 5'-DIPHOSPHATE TRIS SALT
CAS Number 103192-39-8 Molecular Weight 564.33600
Density N/A Boiling Point N/A
Molecular Formula C14H26N6O14P2 Melting Point N/A
MSDS USA Flash Point N/A

 Use of GUANOSINE 5'-DIPHOSPHATE TRIS SALT


Guanosine 5′-diphosphate (GDP) is the diphosphate nucleoside of the purine guanine. GDP and GTP are involved in and may be used to study cell signaling via G-coupled protein receptors (GCPR) and guanine nucleotide exchange factors (GEF) and a variety of GTPases.

 Names

Name 2-amino-2-(hydroxymethyl)propane-1,3-diol,[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C14H26N6O14P2
Molecular Weight 564.33600
Exact Mass 564.09800
PSA 359.89000
Storage condition 20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles5

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The activation of the Rac1 GTPase during cell signalling entails its translocation from the cytosol to membranes, release from sequestering Rho GDP dissociation inhibitors (RhoGDI), and GDP/GTP exchan...

RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.

Genetics 189 , 165-176, (2011)

Heterotrimeric (αβγ) G proteins are crucial components of eukaryotic signal transduction pathways. G-protein-coupled receptors (GPCRs) act as guanine nucleotide exchange factors (GEFs) for Gα subunits...

Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.

J. Biol. Chem. 286 , 35163-35175, (2011)

PDZRhoGEF (PRG) belongs to a small family of RhoA-specific nucleotide exchange factors that mediates signaling through select G-protein-coupled receptors via Gα(12/13) and activates RhoA by catalyzing...

 Synonyms

Guanosine 5 inverted exclamation marka-diphosphate tris salt from Saccharomyces cerevisiae