Guanosine-5'-diphosphate disodium salt

Modify Date: 2024-01-03 16:53:59

Guanosine-5'-diphosphate disodium salt Structure
Guanosine-5'-diphosphate disodium salt structure
Common Name Guanosine-5'-diphosphate disodium salt
CAS Number 7415-69-2 Molecular Weight 487.16
Density N/A Boiling Point 961ºC at 760 mmHg
Molecular Formula C10H13N5Na2O11P2 Melting Point N/A
MSDS USA Flash Point 535ºC

 Use of Guanosine-5'-diphosphate disodium salt


Guanosine 5'-diphosphate disodium salt is a nucleoside diphosphate. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway[1].

 Names

Name Guanosine-5'-diphosphate disodium salt
Synonym More Synonyms

 Guanosine-5'-diphosphate disodium salt Biological Activity

Description Guanosine 5'-diphosphate disodium salt is a nucleoside diphosphate. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway[1].
Related Catalog
References

[1]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.

 Chemical & Physical Properties

Boiling Point 961ºC at 760 mmHg
Molecular Formula C10H13N5Na2O11P2
Molecular Weight 487.16
Flash Point 535ºC
Exact Mass 486.988220
PSA 277.85000
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3.0

 Articles4

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The RasGrf family of mammalian guanine nucleotide exchange factors.

Biochim. Biophys. Acta 1815 , 170-188, (2011)

RasGrf1 and RasGrf2 are highly homologous mammalian guanine nucleotide exchange factors which are able to activate specific Ras or Rho GTPases. The RasGrf genes are preferentially expressed in the cen...

Models for the functions of Arf GAPs.

Semin. Cell. Dev. Biol. 22 , 3-9, (2011)

Arf GAPs (ADP-ribosylation factor GTPase-activating proteins) are essential components of Arf (ADP-ribosylation factor) signaling pathways. Arf GAPs stimulate the hydrolysis of GTP to GDP to transitio...

A novel GDP-dependent pyruvate kinase isozyme from Toxoplasma gondii localizes to both the apicoplast and the mitochondrion.

J. Biol. Chem. 283 , 14041-14052, (2008)

We previously reported a cytosolic pyruvate kinase (EC 2.7.1.40) from Toxoplasma gondii (TgPyKI) that differs from most eukaryotic pyruvate kinases in being regulated by glucose 6-phosphate rather tha...

 Synonyms

5'-GDP-Na
MFCD00084665
GDP.Na2
Guanosine, 5'-(trihydrogen diphosphate), sodium salt (1:2)
5'-GDP,2Na
Disodium 5'-O-{[(hydroxyphosphinato)oxy]phosphinato}guanosine
Einecs 231-026-2
GDP,NA2H
5'-GDP-Na2
5'-GDP 3NA
GUANOSINE-5'-DIPHOSPHORIC ACID,DISODIUM
Guanosine-5'-diphosphatedisodiumsalt
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