sodium,[5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate

Modify Date: 2024-01-16 09:21:39

sodium,[5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate Structure
sodium,[5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate structure
Common Name sodium,[5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate
CAS Number 103226-10-4 Molecular Weight 348.15400
Density N/A Boiling Point N/A
Molecular Formula C9H11FN2NaO8P Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Names

Name sodium,[5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C9H11FN2NaO8P
Molecular Weight 348.15400
Exact Mass 348.01300
PSA 163.98000

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H302-H312-H332-H351
Precautionary Statements P280
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn: Harmful;
Risk Phrases 20/21/22-40
Safety Phrases 22-36/37/39
RIDADR NONH for all modes of transport

 Articles7

More Articles
Dynamic modulation of thymidylate synthase gene expression and fluorouracil sensitivity in human colorectal cancer cells.

PLoS ONE 10(4) , e0123076, (2015)

Biomarkers have revolutionized cancer chemotherapy. However, many biomarker candidates are still in debate. In addition to clinical studies, a priori experimental approaches are needed. Thymidylate sy...

Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding.

Acta Crystallogr. D Biol. Crystallogr. 67 , 60-66, (2011)

Thymidylate synthase (TS) is a well validated target in cancer chemotherapy. Here, a new crystal form of the R163K variant of human TS (hTS) with five subunits per asymmetric part of the unit cell, al...

Novel chemical strategies for thymidylate synthase inhibition.

Curr. Med. Chem. 12 , 191-202, (2005)

Thymidylate synthase (TS) is a well-validated target for cancer chemotherapy. TS was established as the principal target of the widely used anticancer drug 5-fluorouracil (5FU). The 5FU metabolite FdU...

 Synonyms

FdUMP
5-Fluoro-2 inverted exclamation marka-deoxyuridine 5 inverted exclamation marka-monophosphate sodium salt
5-Fluoro-2`-deoxyuridine 5`-Monophosphate Disodium Salt
disodium 5-fluoro-2'-deoxyuridylate
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