H-Leu-Leu-Leu-OH

Modify Date: 2025-08-26 23:42:55

H-Leu-Leu-Leu-OH Structure
H-Leu-Leu-Leu-OH structure
Common Name H-Leu-Leu-Leu-OH
CAS Number 10329-75-6 Molecular Weight 357.48800
Density 1.057g/cm3 Boiling Point 589.6ºC at 760mmHg
Molecular Formula C18H35N3O4 Melting Point N/A
MSDS Chinese USA Flash Point 310.4ºC

 Use of H-Leu-Leu-Leu-OH


(S)-2-((S)-2-((S)-2-Amino-4-methylpentanamido)-4-methylpentanamido)-4-methylpentanoic acid is a leucine derivative[1].

 Names

Name Leu-Leu-Leu
Synonym More Synonyms

 H-Leu-Leu-Leu-OH Biological Activity

Description (S)-2-((S)-2-((S)-2-Amino-4-methylpentanamido)-4-methylpentanamido)-4-methylpentanoic acid is a leucine derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.057g/cm3
Boiling Point 589.6ºC at 760mmHg
Molecular Formula C18H35N3O4
Molecular Weight 357.48800
Flash Point 310.4ºC
Exact Mass 357.26300
PSA 121.52000
LogP 2.98830
Vapour Pressure 1.99E-15mmHg at 25°C
Index of Refraction 1.488
InChIKey DNDWZFHLZVYOGF-KKUMJFAQSA-N
SMILES CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)O

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~%

H-Leu-Leu-Leu-OH Structure

H-Leu-Leu-Leu-OH

CAS#:10329-75-6

Literature: Fermentforschung, vol. 9, p. 528 Chem. Zentralbl., , vol. 99, # II p. 580

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles15

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Inhibition of brain tumor growth by intravenous poly (β-L-malic acid) nanobioconjugate with pH-dependent drug release [corrected].

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Trileucine improves aerosol performance and stability of spray-dried powders for inhalation.

J. Pharm. Sci. 97 , 287-302, (2008)

For particles to be useful medicinal aerosols, not only their aerodynamic diameter has to be on the order of a few micrometers but also they have to be chemically and physically stable. Manufacture of...

Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(β-L-malic acid).

Pharm. Res. 27 , 2317-2329, (2010)

Temozolomide (TMZ) is a pro-drug releasing a DNA alkylating agent that is the most effective drug to treat glial tumors when combined with radiation. TMZ is toxic, and therapeutic dosages are limited ...

 H-Leu-Leu-Leu-OHBioassay

View more

Name: Bitter threshold value
Source: ChEMBL
Target: N/A
External Id: CHEMBL848034
Name: Noncompetitive inhibition of nitrogen-starved wild type sigma1278b yeast Gap1-mediate...
Source: ChEMBL
Target: General amino-acid permease GAP1
External Id: CHEMBL1228073
Name: Activation of nitrogen-starved wild type sigma1278b yeast Gap1-mediated amino acid up...
Source: ChEMBL
Target: General amino-acid permease GAP1
External Id: CHEMBL1228070
Name: Partition coefficient (logP)
Source: ChEMBL
Target: N/A
External Id: CHEMBL636806
Total 4, Current Page 1 of 1
1

 Synonyms

L-LEUCY-L-LEUCYL-L-LEUCINE
tri-leucine
LEU-LEU-LEU
MFCD00038309
Leucylleucylleucin
Leu-leu-leucrystalline
L-LEUCYL-L-LEUCYL-L-LEUCINE
L-LEUCYLLEUCYLLEUCINE
leucyl-leucyl-leucine
H-LEU-LEU-LEU-OH
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