2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride

Modify Date: 2024-01-14 16:11:16

2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride Structure
2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride structure
Common Name 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride
CAS Number 1035373-85-3 Molecular Weight 260.20112
Density N/A Boiling Point N/A
Molecular Formula C10H23Cl2NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride


2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-(6-chloro-hexyloxy)-ethoxy]-ethylamine hydrochloride
Synonym More Synonyms

  Biological Activity

Description 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C10H23Cl2NO2
Molecular Weight 260.20112
Exact Mass 259.110596

 Safety Information

Hazard Codes Xi

 Synonyms

2-{2-[(6-Chlorohexyl)oxy]ethoxy}ethanamine hydrochloride (1:1)
Ethanamine, 2-[2-[(6-chlorohexyl)oxy]ethoxy]-, hydrochloride (1:1)
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