5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid

Modify Date: 2025-08-26 03:38:59

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure
5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid structure
 Common Name 5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid
CAS Number 103772-14-1 Molecular Weight 298.21700
Density 1.762g/cm3 Boiling Point 512.4ºC at 760mmHg
Molecular Formula C13H9F3N2O3 Melting Point N/A
MSDS N/A Flash Point 263.7ºC

 Names

Name 5-amino-1-cyclopropyl-6,7,8-trifluoro-4-oxoquinoline-3-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.762g/cm3
Boiling Point 512.4ºC at 760mmHg
Molecular Formula C13H9F3N2O3
Molecular Weight 298.21700
Flash Point 263.7ºC
Exact Mass 298.05700
PSA 85.32000
LogP 2.61530
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.68

 Synthetic Route

1-CYCLOPROPYL-5-AMIDO-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3- QUINOLINECARBOXYLIC ACID ETHYL ESTER structure

1-CYCLOPROPYL-5...

CAS#:103772-13-0

~97%

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure

5-Amino-l-Cyclo...

CAS#:103772-14-1

Literature: Domagala; Bridges; Culbertson; Gambino; Hagen; Karrick; Porter; Sanchez; Sesnie; Spense; Szotek; Wemple Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1142 - 1154
ethyl 5-(benzylamino)-1-cyclopropyl-6,7,8-trifluoro-4(1H)-oxoquinoline-3-carboxylate structure

ethyl 5-(benzyl...

CAS#:110872-04-3

~93%

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure

5-Amino-l-Cyclo...

CAS#:103772-14-1

Literature: Miyamoto, Teruyuki; Matsumoto, Jun-ichi; Chiba, Katsumi; Egawa, Hiroshi; Shibamori, Koh-ichiro; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1645 - 1656
1-cyclopropyl-5,6,7,8-tetrafluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid,ethyl ester structure

1-cyclopropyl-5...

CAS#:107564-02-3

~%

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure

5-Amino-l-Cyclo...

CAS#:103772-14-1

Literature: Cociorva, Oana M.; Li, Bei; Nomanbhoy, Tyzoon; Li, Qiang; Nakamura, Ayako; Nakamura, Kai; Nomura, Masahiro; Okada, Kyoko; Seto, Shigeki; Yumoto, Kazuhiro; Liyanage, Marek; Zhang, Melissa C.; Aban, Arwin; Leen, Brandon; Szardenings, Anna Katrin; Rosenblum, Jonathan S.; Kozarich, John W.; Kohno, Yasushi; Shreder, Kevin R. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5948 - 5951
1-CYCLOPROPYL-5-NITRO-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3- QUINOLINECARBOXYLIC ACID ETHYL ESTER structure

1-CYCLOPROPYL-5...

CAS#:103772-12-9

~%

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure

5-Amino-l-Cyclo...

CAS#:103772-14-1

Literature: Domagala; Bridges; Culbertson; Gambino; Hagen; Karrick; Porter; Sanchez; Sesnie; Spense; Szotek; Wemple Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1142 - 1154
2,3,4,5-Tetrafluoro-6-nitrobenzoic acid structure

2,3,4,5-Tetrafl...

CAS#:16583-08-7

~%

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure

5-Amino-l-Cyclo...

CAS#:103772-14-1

Literature: Domagala; Bridges; Culbertson; Gambino; Hagen; Karrick; Porter; Sanchez; Sesnie; Spense; Szotek; Wemple Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1142 - 1154
2,3,4,5-Tetrafluoro-6-nitrobenzoyl chloride structure

2,3,4,5-Tetrafl...

CAS#:103772-10-7

~%

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure

5-Amino-l-Cyclo...

CAS#:103772-14-1

Literature: Domagala; Bridges; Culbertson; Gambino; Hagen; Karrick; Porter; Sanchez; Sesnie; Spense; Szotek; Wemple Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1142 - 1154
2-nitro-3,4,5,6-tetrafluoro-β-oxobenzenepropanoic acid,ethyl ester structure

2-nitro-3,4,5,6...

CAS#:103772-11-8

~%

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure

5-Amino-l-Cyclo...

CAS#:103772-14-1

Literature: Domagala; Bridges; Culbertson; Gambino; Hagen; Karrick; Porter; Sanchez; Sesnie; Spense; Szotek; Wemple Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1142 - 1154
ethyl α-(ethoxymethylene)-2,3,4,5-tetrafluoro-6-nitro-β-oxobenzenepropanoate structure

ethyl α-(ethoxy...

CAS#:104885-01-0

~%

5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid Structure

5-Amino-l-Cyclo...

CAS#:103772-14-1

Literature: Domagala; Bridges; Culbertson; Gambino; Hagen; Karrick; Porter; Sanchez; Sesnie; Spense; Szotek; Wemple Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1142 - 1154

 Synonyms

1-Cyclopropyl-5,6,8-trifluoro-1,4-dihydro-7-(cis-3,5-dimethyl-1-piperazinyl)-4-oxo-quinoline-3-carboxylic acid
1-cyclopropyl-5-amino-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid L
1-cyclopropyl-5-amino-6,7,8-trifluoro-4-oxo-1,4-dihydro-3-quinoline-carboxylic acid
ORBIFLOXACIN
Orbax
5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid
1-cyclopropyl-5,6,8-trifluoro-7-(cis-3,5-dimethyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
1-Cyclopropyl-5,6,8-trifluoro-1,4-dihydro-7-(cis-3,5-dimethylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
1-cyclopropyl-5-amino-6,7,8-trifluoro-4-oxo-1,4-dihydroquinolin-3-carboxylic acid
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Chemsrc provides CAS#:103772-14-1 MSDS, density, melting point, boiling point, structure, etc. Its name is 5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid>> amp version: 5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid

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