4,8-Ethenopyrrolo[3',4':3,4]cyclobut[1,2-f]isoindole-1,3,5,7(2H,6H)-tetrone,3a,3b,4,4a,7a,8,8a,8b-octahydro-, (3aR,3bS,4R,4aR,7aS,8S,8aR,8bS)-rel-

Modify Date: 2024-01-14 10:38:26

4,8-Ethenopyrrolo[3',4':3,4]cyclobut[1,2-f]isoindole-1,3,5,7(2H,6H)-tetrone,3a,3b,4,4a,7a,8,8a,8b-octahydro-, (3aR,3bS,4R,4aR,7aS,8S,8aR,8bS)-rel- structure	Common Name	4,8-Ethenopyrrolo[3',4':3,4]cyclobut[1,2-f]isoindole-1,3,5,7(2H,6H)-tetrone,3a,3b,4,4a,7a,8,8a,8b-octahydro-, (3aR,3bS,4R,4aR,7aS,8S,8aR,8bS)-rel-
	CAS Number	10403-51-7	Molecular Weight	272.25600
	Density	1.518g/cm3	Boiling Point	618.2ºC at 760mmHg
	Molecular Formula	C₁₄H₁₂N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	270ºC

Name	Mitindomide
Synonym	More Synonyms

Density	1.518g/cm3
Boiling Point	618.2ºC at 760mmHg
Molecular Formula	C₁₄H₁₂N₂O₄
Molecular Weight	272.25600
Flash Point	270ºC
Exact Mass	272.08000
PSA	92.34000
Vapour Pressure	3.26E-15mmHg at 25°C
Index of Refraction	1.627

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YD2143000

CAS REGISTRY NUMBER :: 10403-51-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H12-N2-O4

MOLECULAR WEIGHT :: 272.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,38,1991

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,38,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 193 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986

Maleimide

CAS#:541-59-3

benzene

CAS#:71-43-2

4,8-Ethenopyrro...

CAS#:10403-51-7

Literature: Bryce-Smith, D.; Gilbert, A.; Al-Jalal, N.; Deshpande, R.R.; Grzonka, J.; et al. Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1983 , vol. 38, # 9 p. 1101 - 1112

Precursor 2
CAS#:541-59-3 Maleimide CAS#:71-43-2 benzene
DownStream 0

Benzenebismaleimide adduct

tricyclo<4.2.2.02,5>dec-9-ene-3,4,7,8-tetracarboxylic acid diimide

3a,3b,4,4a,7a,8,8b-octahydro-4,8-ethenopyrrolo[3',4':3,4]cyclobut[1,2-f]isoindole-1,3,5,7[2H,6H]tetrone

Dichloromethane
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Polyacrylic acid
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sodium carbonate
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Silicon dioxide
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Triethanolamine
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Demeton
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Water
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4-(4-Piperidinyl)morpholine dihydrochloride
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Diclofenac sodium
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Budesonide
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4,8-Ethenopyrrolo[3',4':3,4]cyclobut[1,2-f]isoindole-1,3,5,7(2H,6H)-tetrone,3a,3b,4,4a,7a,8,8a,8b-octahydro-, (3aR,3bS,4R,4aR,7aS,8S,8aR,8bS)-rel-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms