Maleimide

Modify Date: 2025-08-20 15:43:09

Maleimide structure	Common Name	Maleimide
	CAS Number	541-59-3	Molecular Weight	97.072
	Density	1.4±0.1 g/cm3	Boiling Point	264.4±23.0 °C at 760 mmHg
	Molecular Formula	C₄H₃NO₂	Melting Point	91-93 °C(lit.)
	MSDS	Chinese USA	Flash Point	113.7±22.6 °C
	Symbol	GHS05, GHS06	Signal Word	Danger

Name	maleimide
Synonym	More Synonyms

Density	1.4±0.1 g/cm3
Boiling Point	264.4±23.0 °C at 760 mmHg
Melting Point	91-93 °C(lit.)
Molecular Formula	C₄H₃NO₂
Molecular Weight	97.072
Flash Point	113.7±22.6 °C
Exact Mass	97.016380
PSA	46.17000
LogP	-0.69
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.606
InChIKey	PEEHTFAAVSWFBL-UHFFFAOYSA-N
SMILES	O=C1C=CC(=O)N1
Storage condition	Refrigerator
Water Solubility	SOLUBLE

Maleimide MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ON4800000

CHEMICAL NAME :: Maleimide

CAS REGISTRY NUMBER :: 541-59-3

BEILSTEIN REFERENCE NO. :: 0106910

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C4-H3-N-O2

MOLECULAR WEIGHT :: 97.08

WISWESSER LINE NOTATION :: T5VMVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 40(11),109,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7766 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - hemorrhage Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - other changes

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,151,1978 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 750 ug/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 3100 ug/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H301-H314-H317
Precautionary Statements	P280-P301 + P310-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25;R36/37/38;R43
Safety Phrases	S26-S36/37/39-S45-S37/39-S28A
RIDADR	UN 2923 8/PG 2
WGK Germany	3
RTECS	ON4800000
Packaging Group	III
Hazard Class	8
HS Code	29251995

Precursor 10
CAS#:108-31-6 Maleic anhydride CAS#:373-02-4 Nickel-acetic a... CAS#:60-32-2 6-Aminocaproic acid CAS#:557-24-4 (Z)-4-Amino-4-o...
CAS#:55750-48-6 METHYL 2,5-DIOX... CAS#:60311-02-6 Sulforhodamine 101 CAS#:7647-01-0 Hydrochloric acid CAS#:5926-51-2 Bromomaleic anh...
CAS#:20781-20-8 2,4-Dimethoxybe... CAS#:60-29-7 Diethyl ether
DownStream 10
CAS#:557-24-4 (Z)-4-Amino-4-o... CAS#:55750-49-7 Ethyl 2,5-Dioxo... CAS#:370879-53-1 cis-5-Benzyltet... CAS#:55750-48-6 METHYL 2,5-DIOX...
CAS#:34314-63-1 3-oxauracil CAS#:5063-96-7 N-(Hydroxymethy... CAS#:4379-54-8 2,3-Naphthalene... CAS#:941-69-5 N-Phenylmaleimide
CAS#:20458-51-9 1-NONYL-PYRROLE... CAS#:198474-05-4 PF-06840003

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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G protein-coupled receptors (GPCRs) represent the largest family of transmembrane signaling proteins, and they are considered major targets of approximately half of all therapeutic agents. Human melan...

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: Kinase Inhibition Assay from Article 10.1021/jm040895g: "SAR and 3D-QSAR studies on t...
Source: BindingDB
Target: N/A
External Id: BindingDB_987_1

Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

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MFCD00005494

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Maleimide
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Maleimide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Maleimide
Price: ￥848.0/25g ￥248.0/5g
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

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Maleimide

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.