MCC

Modify Date: 2024-01-12 11:36:01

MCC Structure
MCC structure
Common Name MCC
CAS Number 104676-09-7 Molecular Weight 236.27
Density N/A Boiling Point N/A
Molecular Formula C12H16N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MCC


MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].

 Names

Name MCC

 MCC Biological Activity

Description MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].
Related Catalog
In Vitro Antibody-drug conjugates (ADCs) are potent cytotoxic drugs linked to antibodies through chemical linkers, and allow specific targeting of drugs to neoplastic cells. Anti-CD22-MCC-DM1 is broadly effective in vitro against multiple NHL cell lines[1].
References

[1]. Polson AG, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia. 2010;24(9):1566-1573.

 Chemical & Physical Properties

Molecular Formula C12H16N2O3
Molecular Weight 236.27
Storage condition 2-8°C