NSC 694621

Modify Date: 2024-04-09 15:08:29

NSC 694621 structure	Common Name	NSC 694621
	CAS Number	104857-29-6	Molecular Weight	258.30
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₀N₂O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NSC 694621

NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1].

Name	NSC 694621

Description	NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Acetyltransferase
Target	IC50: 5.71 µM (PCAF/H31-21)[1].
In Vitro	NSC 694621 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells[1]. Cell Proliferation Assay[1] Cell Line: SK-N-SH, HCT116 cells Concentration: 25 µM Incubation Time: 72 h Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI50 of 19.2 µM and growth inhibition of 29%, respectively.
References	[1]. Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89.

Molecular Formula	C₁₃H₁₀N₂O₂S
Molecular Weight	258.30

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NSC 694621
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Purity: 99.0%
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