β-ketoacyl-[acyl-carrier-protein] synthase III
Modify Date: 2024-01-15 07:00:49
![β-ketoacyl-[acyl-carrier-protein] synthase III Structure](https://www.chemsrc.com/caspic/default.png)
β-ketoacyl-[acyl-carrier-protein] synthase III structure
|
Common Name | β-ketoacyl-[acyl-carrier-protein] synthase III | ||
|---|---|---|---|---|
| CAS Number | 1048646-78-1 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of β-ketoacyl-[acyl-carrier-protein] synthase IIIInvolved in the dissociated (or type II) fatty-acid biosynthesis system that occurs in plants and bacteria. In contrast to EC 2.3.1.41 (β-ketoacyl-ACP synthase I) and EC 2.3.1.179 (β-ketoacyl-ACP synthase II), this enzyme specifically uses CoA thioesters rather than acyl-ACP as the primer. In addition to the above reaction, the enzyme can also catalyse the reaction of EC 2.3.1.38, [acyl-carrier-protein] S-acetyltransferase, but to a much lesser extent. The enzyme is responsible for initiating both straight- and branched-chain fatty-acid biosynthesis, with the substrate specificity in an organism reflecting the fatty-acid composition found in that organism. For example, Streptococcus pneumoniae, a Gram-positive bacterium, is able to use both straight- and branched-chain (C4-C6) acyl-CoA primers whereas Escherichia coli, a Gram-negative organism, uses primarily short straight-chain acyl CoAs, with a preference for acetyl-CoA. Reaction: acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 |
| Name | β-ketoacyl-[acyl-carrier-protein] synthase III |
|---|---|
| Synonym | More Synonyms |
| Description | Involved in the dissociated (or type II) fatty-acid biosynthesis system that occurs in plants and bacteria. In contrast to EC 2.3.1.41 (β-ketoacyl-ACP synthase I) and EC 2.3.1.179 (β-ketoacyl-ACP synthase II), this enzyme specifically uses CoA thioesters rather than acyl-ACP as the primer. In addition to the above reaction, the enzyme can also catalyse the reaction of EC 2.3.1.38, [acyl-carrier-protein] S-acetyltransferase, but to a much lesser extent. The enzyme is responsible for initiating both straight- and branched-chain fatty-acid biosynthesis, with the substrate specificity in an organism reflecting the fatty-acid composition found in that organism. For example, Streptococcus pneumoniae, a Gram-positive bacterium, is able to use both straight- and branched-chain (C4-C6) acyl-CoA primers whereas Escherichia coli, a Gram-negative organism, uses primarily short straight-chain acyl CoAs, with a preference for acetyl-CoA. Reaction: acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 |
|---|
| No Any Chemical & Physical Properties |
| EC 2.3.1.180 |
| 3-oxoacyl:ACP synthase III |
| 3-ketoacyl-acyl carrier protein synthase III |
| KASIII |
| KAS III |
| FabH |
| β-ketoacyl-acyl carrier protein synthase III |
| β-ketoacyl-ACP synthase III |
| β-ketoacyl (acyl carrier protein) synthase III |
| acetyl-CoA:malonyl-[acyl-carrier-protein] C-acyltransferase |