Naspm (trihydrochloride)

Modify Date: 2025-08-25 18:06:36

Naspm (trihydrochloride) Structure
Naspm (trihydrochloride) structure
 Common Name Naspm (trihydrochloride)
CAS Number 1049731-36-3 Molecular Weight 479.91400
Density N/A Boiling Point N/A
Molecular Formula C22H37Cl3N4O Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Naspm (trihydrochloride)


Naspm (1-Naphthyl acetyl spermine) trihydrochloride, a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.

 Names

Name N-[3-({4-[(3-Aminopropyl)amino]butyl}amino)propyl]-2-(1-naphthyl) acetamide trihydrochloride
Synonym More Synonyms

 Naspm (trihydrochloride) Biological Activity

Description Naspm (1-Naphthyl acetyl spermine) trihydrochloride, a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
Related Catalog
References

[1]. Koike M, et al. Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci Res. 1997 Sep;29(1):27-36.

 Chemical & Physical Properties

Molecular Formula C22H37Cl3N4O
Molecular Weight 479.91400
Exact Mass 478.20300
PSA 82.67000
LogP 6.92520
Storage condition 2-8℃

 Synonyms

1-Naphthylacetyl Spermine Trihydrochloride
Naspm (trihydrochloride)
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