N,N'-Diethylthiourea

Modify Date: 2024-01-02 15:52:34

N,N'-Diethylthiourea Structure
N,N'-Diethylthiourea structure
Common Name N,N'-Diethylthiourea
CAS Number 105-55-5 Molecular Weight 132.22700
Density 1,12 g/cm3 Boiling Point 169.2ºC at 760 mmHg
Molecular Formula C5H12N2S Melting Point 76-78 °C(lit.)
MSDS Chinese USA Flash Point 186 °C
Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger

 Names

Name N,N'-Diethylthiourea
Synonym More Synonyms

 Chemical & Physical Properties

Density 1,12 g/cm3
Boiling Point 169.2ºC at 760 mmHg
Melting Point 76-78 °C(lit.)
Molecular Formula C5H12N2S
Molecular Weight 132.22700
Flash Point 186 °C
Exact Mass 132.07200
PSA 56.15000
LogP 1.27210
Vapour Pressure 1.56mmHg at 25°C
Index of Refraction 1.505
Stability Stable. May be air sensitive. Incompatible with strong oxidizing agents.
Water Solubility 38 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS9800000
CHEMICAL NAME :
Urea, 1,3-diethyl-2-thio-
CAS REGISTRY NUMBER :
105-55-5
BEILSTEIN REFERENCE NO. :
0773905
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C5-H12-N2-S
MOLECULAR WEIGHT :
132.25
WISWESSER LINE NOTATION :
SUYM1&M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
62 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
11 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
550 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 356,85,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84809 No. of Facilities: 487 (estimated) No. of Industries: 6 No. of Occupations: 8 No. of Employees: 11186 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84809 No. of Facilities: 1141 (estimated) No. of Industries: 24 No. of Occupations: 28 No. of Employees: 11484 (estimated) No. of Female Employees: 739 (estimated)

 Safety Information

Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger
Hazard Statements H302 + H312-H317-H318-H372-H412
Precautionary Statements P260-P280-P301 + P312 + P330-P305 + P351 + P338 + P310
Target Organs Thyroid.
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R40
Safety Phrases S45-S36/37
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS YS9800000
HS Code 29309070

 Synthetic Route

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

1,3-diethylthiourea
MFCD00004925
1,3-Diethyl-2-thiourea
EINECS 203-308-5
N,N‘-Diethylthiourea
DETU
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