(R,R)-Reboxetine mesylate

Modify Date: 2025-08-25 19:56:18

(R,R)-Reboxetine mesylate Structure
(R,R)-Reboxetine mesylate structure
 Common Name (R,R)-Reboxetine mesylate
CAS Number 105017-39-8 Molecular Weight 409.50
Density N/A Boiling Point N/A
Molecular Formula C20H27NO6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R,R)-Reboxetine mesylate


(R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for alpha-adrenergic and muscarinic receptors and low toxicity in animals[1][2].

 Names

Name (R,R)-Reboxetine mesylate

 (R,R)-Reboxetine mesylate Biological Activity

Description (R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for alpha-adrenergic and muscarinic receptors and low toxicity in animals[1][2].
Related Catalog
Target

α adrenergic receptor

Muscarinic Receptors

References

[1]. Wienkers LC, et al. Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes. Drug Metab Dispos. 1999 Nov;27(11):1334-40.  

[2]. Dostert P, et al. Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor. Eur Neuropsychopharmacol. 1997 Apr;7 Suppl 1:S23-35; discussion S71-3.  

 Chemical & Physical Properties

Molecular Formula C20H27NO6S
Molecular Weight 409.50
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