3,5-Difluorophenylacetic acid

Modify Date: 2024-01-08 13:16:28

3,5-Difluorophenylacetic acid Structure
3,5-Difluorophenylacetic acid structure
Common Name 3,5-Difluorophenylacetic acid
CAS Number 105184-38-1 Molecular Weight 172.129
Density 1.4±0.1 g/cm3 Boiling Point 245.0±25.0 °C at 760 mmHg
Molecular Formula C8H6F2O2 Melting Point 68-70 °C(lit.)
MSDS Chinese USA Flash Point 102.0±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3,5-Difluorophenylacetic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 245.0±25.0 °C at 760 mmHg
Melting Point 68-70 °C(lit.)
Molecular Formula C8H6F2O2
Molecular Weight 172.129
Flash Point 102.0±23.2 °C
Exact Mass 172.033585
PSA 37.30000
LogP 1.65
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.508

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S36/37/39-S22-S22/26/36/37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2916399090

 Synthetic Route

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3,5-Difluorophenylacetic acid Structure

3,5-Difluorophe...

CAS#:105184-38-1

Literature: Synthesis, , # 12 p. 1411 - 1414

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles3

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Org. Biomol. Chem. 3(13) , 2450-7, (2005)

Inhibition of gamma-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce pathogenic Abeta peptides, is an attractive approach for the treatment ...

Synthesis of a tetrahydroimidazo [2', 1': 2, 3] thiazolo [5, 4-c] pyridine derivative with Met inhibitory activity. Amat M, et al.

ARKIVOC 3 , 145-151, (2010)

Synthesis of dihalophenylacetic acids using aromatic nucleophilic substitution strategy. Kowalczyk BA.

Synthesis 1997(12) , 1411-14, (1997)

 Synonyms

MFCD00010316
(3,5-Difluorophenyl)acetic acid
Benzeneacetic acid, 3,5-difluoro-
2-(3,5-difluorophenyl)acetic acid
QV1R CF EF
3,5-Difluorobenzeneacetic acid
3,5-Difluorophenylacetic Acid
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