N-Hydroxysulfosuccinimide sodium

Modify Date: 2024-01-02 12:02:10

N-Hydroxysulfosuccinimide sodium Structure
N-Hydroxysulfosuccinimide sodium structure
Common Name N-Hydroxysulfosuccinimide sodium
CAS Number 106627-54-7 Molecular Weight 217.132
Density N/A Boiling Point N/A
Molecular Formula C4H4NNaO6S Melting Point 250 °C (dec.)(lit.)
MSDS USA Flash Point N/A

 Use of N-Hydroxysulfosuccinimide sodium


N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name N-Hydroxysulfosuccinimide sodium salt
Synonym More Synonyms

 N-Hydroxysulfosuccinimide sodium Biological Activity

Description N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Melting Point 250 °C (dec.)(lit.)
Molecular Formula C4H4NNaO6S
Molecular Weight 217.132
Exact Mass 216.965698
PSA 123.19000
Storage condition 0-6°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2925190090

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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 Synonyms

3-Pyrrolidinesulfonic acid, 1-hydroxy-2,5-dioxo-, sodium salt (1:1)
Sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate
Hydroxy-2,5-dioxopyrrolidine-3-sulfonicacid sodium salt
N-Hydroxysulfosuccinimide sodiumsalt
Sodium 1-hydroxy-2,5-dioxo-3-pyrrolidinesulfonate
sodium,1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate
N-Hydroxysulfosuccinimide Sodium Salt
MFCD00217065
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