Lintopride

Modify Date: 2024-01-20 22:34:47

Lintopride Structure
Lintopride structure
Common Name Lintopride
CAS Number 107429-63-0 Molecular Weight 310.77900
Density 1.35g/cm3 Boiling Point 494.1ºC at 760 mmHg
Molecular Formula C14H19ClN4O2 Melting Point N/A
MSDS N/A Flash Point 252.6ºC

 Use of Lintopride


Lintopride is a 5HT4 antagonist with moderate 5HT3 antagonist properties.

 Names

Name 4-amino-5-chloro-N-[(1-ethyl-4,5-dihydroimidazol-2-yl)methyl]-2-methoxybenzamide
Synonym More Synonyms

 Lintopride Biological Activity

Description Lintopride is a 5HT4 antagonist with moderate 5HT3 antagonist properties.
Related Catalog
Target

5HT4[1]

In Vitro Lintopride significantly increases the lower oesophageal sphincter basal tone without affecting lower oesophageal sphincter physiological relaxation after swallowing. Peristaltic waves are also enhanced by Lintopride[1].
References

[1]. Delvaux M, et al. The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9.

 Chemical & Physical Properties

Density 1.35g/cm3
Boiling Point 494.1ºC at 760 mmHg
Molecular Formula C14H19ClN4O2
Molecular Weight 310.77900
Flash Point 252.6ºC
Exact Mass 310.12000
PSA 83.44000
LogP 1.92410
Vapour Pressure 6.62E-10mmHg at 25°C
Index of Refraction 1.618
Storage condition 2-8℃

 Synonyms

UNII-C2R0GEU722
Lintopridum [INN-Latin]
Lintoprida [INN-Spanish]
Lintopridum
Lintoprida
Lintopride
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