RH 421
RH 421 structure
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Common Name | RH 421 | ||
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| CAS Number | 107610-19-5 | Molecular Weight | 498.72000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H42N2O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of RH 421RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase[1]. |
| Name | 4-[4-[(1E,3E)-4-[4-(dipentylamino)phenyl]buta-1,3-dienyl]pyridin-1-ium-1-yl]butane-1-sulfonate |
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| Synonym | More Synonyms |
| Description | RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C29H42N2O3S |
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| Molecular Weight | 498.72000 |
| Exact Mass | 498.29200 |
| PSA | 72.70000 |
| LogP | 7.29370 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
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Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore.
Biochim. Biophys. Acta 1848(1 Pt A) , 192-9, (2015) The polyene antifungal antibiotic nystatin confers its biological activity by forming pores in the membranes of target cells. Exposure of only one side of the membrane to nystatin is more relevant tha... |
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[The effects of RH 421 on the activity of amphotericin B in cell and model membranes].
Tsitologiia 55(2) , 136-9, (2013) The combined action of polyene macrolide antibiotic amphotericin B and styryl dye RH 421 in model lipid membranes and in yeast Saccharomyces cerevisiae has been studied. RH 421 insertion inti the ergo... |
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Probing amphotericin B single channel activity by membrane dipole modifiers.
PLoS ONE 7(1) , e30261, (2012) The effects of dipole modifiers and their structural analogs on the single channel activity of amphotericin B in sterol-containing planar phosphocholine membranes are studied. It is shown that the add... |
| MFCD00467839 |
| Neurodye RH 421 |
| RH 421 |
| 4-{4-[4-(Dipentylamino)phenyl]-1,3-butadienyl}-1-(4-sulfobutyl)pyridinium hydroxide |