N-Boc-PEG4-bromide

Modify Date: 2024-01-04 13:41:49

N-Boc-PEG4-bromide Structure
N-Boc-PEG4-bromide structure
Common Name N-Boc-PEG4-bromide
CAS Number 1076199-21-7 Molecular Weight 356.25300
Density N/A Boiling Point 422.1±35.0°C at 3 mmHg
Molecular Formula C13H26BrNO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Boc-PEG4-bromide


N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name tert-butyl N-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethyl]carbamate
Synonym More Synonyms

 N-Boc-PEG4-bromide Biological Activity

Description N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Jan Anderl, et al. Amatoxin-Conjugates with Improved Linkers. US20130259880A1

 Chemical & Physical Properties

Boiling Point 422.1±35.0°C at 3 mmHg
Molecular Formula C13H26BrNO5
Molecular Weight 356.25300
Exact Mass 355.09900
PSA 69.51000
LogP 2.16020

 Synonyms

13-Bromo-5,8,11-trioxa-2-azatridecanoic Acid 1,1-Dimethylethyl Ester
1-Boc-amino-3,6,9-trioxaundecanyl-11-bromide
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