N-Boc-PEG4-alcohol

Modify Date: 2024-01-06 14:42:34

N-Boc-PEG4-alcohol Structure
N-Boc-PEG4-alcohol structure
 Common Name N-Boc-PEG4-alcohol
CAS Number 106984-09-2 Molecular Weight 293.35700
Density 1.078g/cm3 Boiling Point 414ºC at 760mmHg
Molecular Formula C13H27NO6 Melting Point N/A
MSDS N/A Flash Point 204.2ºC

 Use of N-Boc-PEG4-alcohol


PROTAC Linker 12 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 12 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name 1-Boc-amino-3,6,9-trioxaundecanyl-11-ol
Synonym More Synonyms

 N-Boc-PEG4-alcohol Biological Activity

Description PROTAC Linker 12 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 12 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.078g/cm3
Boiling Point 414ºC at 760mmHg
Molecular Formula C13H27NO6
Molecular Weight 293.35700
Flash Point 204.2ºC
Exact Mass 293.18400
PSA 86.25000
LogP 0.94410
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.459

 Safety Information

Hazard Codes Xn
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

tert-butyl N-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]carbamate
N-Boc-PEG4-alcohol
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Chemsrc provides N-Boc-PEG4-alcohol(CAS#:106984-09-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of N-Boc-PEG4-alcohol are included as well.>> amp version: N-Boc-PEG4-alcohol

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