Eupalinolide K
Eupalinolide K structure
|
Common Name | Eupalinolide K | ||
|---|---|---|---|---|
| CAS Number | 108657-10-9 | Molecular Weight | 362.417 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 574.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H26O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 201.5±23.6 °C | |
Use of Eupalinolide KEupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1]. |
Summary: Eupalinolide K (Chinese name: 野马追内酯K, CAS number: 108657-10-9, molecular formula: C20H26O6, molecular weight: 362.417) is a powder with a boiling point of 574.4±50.0 °C and a density of 1.2±0.1 g/cm3. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1]. |
|---|---|
| Related Catalog | |
| Target |
STAT3 |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 574.4±50.0 °C at 760 mmHg |
| Molecular Formula | C20H26O6 |
| Molecular Weight | 362.417 |
| Flash Point | 201.5±23.6 °C |
| Exact Mass | 362.172943 |
| PSA | 93.06000 |
| LogP | 2.29 |
| Vapour Pressure | 0.0±3.6 mmHg at 25°C |
| Index of Refraction | 1.557 |
| InChIKey | APOGLVUGPAVNAP-GIDICUODSA-N |
| SMILES | C=C1C(=O)OC2C=C(C)C(O)CC=C(C)CC(OC(=O)C(C)=CCO)C12 |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3β-hydroxy-8β-[4'-hydroxytigloyloxy]costunolide |
| (2E)-4-hydroxy-2-methylbut-2-enoic acid (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester |
| (3aR,4S,6Z,9S,10Z,11aR)-9-Hydroxy-6,10-dimethyl-3-methylene-2-oxo-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methyl-2-butenoate |
| eupalinolide K |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: LogP of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is 2.29. |
| Q: What is the SMILES notation of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: SMILES notation of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is C=C1C(=O)OC2C=C(C)C(O)CC=C(C)CC(OC(=O)C(C)=CCO)C12. |
| Q: What are the uses of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: Main uses of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone: Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1]. |
| Q: What is the molecular formula of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: Molecular formula of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is C20H26O6. |
| Q: What is the English name of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: The English name of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone. |
| Q: What is the InChIKey of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: InChIKey of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is APOGLVUGPAVNAP-GIDICUODSA-N. |
| Q: What is the polar surface area (PSA) of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: Polar surface area (PSA) of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is 93.06000. |
| Q: What is the CAS number of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: CAS number of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is 108657-10-9. |
| Q: What is the boiling point of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: Boiling point of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is 574.4±50.0 °C at 760 mmHg. |
| Q: What is the molecular weight of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone? |
| A: Molecular weight of (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone is 362.417. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| naturewill |