2-Methylaminoethanol

Modify Date: 2024-01-02 10:15:40

2-Methylaminoethanol Structure
2-Methylaminoethanol structure
Common Name 2-Methylaminoethanol
CAS Number 109-83-1 Molecular Weight 75.110
Density 0.9±0.1 g/cm3 Boiling Point 159.9±13.0 °C at 760 mmHg
Molecular Formula C3H9NO Melting Point -3 °C
MSDS Chinese USA Flash Point 73.9±0.0 °C
Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger

 Names

Name N-methylethanolamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 159.9±13.0 °C at 760 mmHg
Melting Point -3 °C
Molecular Formula C3H9NO
Molecular Weight 75.110
Flash Point 73.9±0.0 °C
Exact Mass 75.068413
PSA 32.26000
LogP -0.96
Vapour density 2.6 (vs air)
Vapour Pressure 0.9±0.6 mmHg at 25°C
Index of Refraction 1.440
Stability Stable. Combustible. Incompatible with oxidizing agents.
Water Solubility miscible

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KL6650000
CHEMICAL NAME :
Ethanol, 2-(methylamino)-
CAS REGISTRY NUMBER :
109-83-1
BEILSTEIN REFERENCE NO. :
1071196
LAST UPDATED :
199806
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C3-H9-N-O
MOLECULAR WEIGHT :
75.13
WISWESSER LINE NOTATION :
Q2M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/20/1972 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2340 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1330 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 12,486,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1802 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - other changes
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 225,428,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1070 uL/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536158 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4016 No. of Facilities: 7733 (estimated) No. of Industries: 36 No. of Occupations: 28 No. of Employees: 39013 (estimated) No. of Female Employees: 11887 (estimated)

 Safety Information

Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger
Hazard Statements H302 + H312-H314-H335-H373
Precautionary Statements P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Target Organs Epididymus, Kidney, Liver, Testes, ovary, spleen
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R21/22;R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2735 8/PG 2
WGK Germany 1
RTECS KL6650000
Packaging Group III
Hazard Class 8
HS Code 29221980

 Synthetic Route

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

MFCD00002839
2-Hydroxypropanamine
2-(Methylamino)ethanol
(RS)-1-Amino-2-hydroxypropane
1-Amino-2-hydroxypropane
propan-2-ol, 1-amino-
N-Methylethanolamine
2-Methylaminoethanol
(±)-1-Amino-2-propanol
1-Aminopropan-2-ol
(RS)-1-amino-2-propanol
2-Propanol, 1-amino- (8CI,9CI)
UNII:UE40BY1BZW
2-Hydroxy-1-propylamine
2-Propanol, 1-amino-
EINECS 203-710-0
(±)-Isopropanolamine
1-Amino-2-propanol
2-Propanol, 1-amino-, (±)-
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