Oseltamivir D3

Modify Date: 2024-01-22 08:27:48

Oseltamivir D3 Structure
Oseltamivir D3 structure
Common Name Oseltamivir D3
CAS Number 1093851-61-6 Molecular Weight 315.42300
Density N/A Boiling Point N/A
Molecular Formula C16H25D3N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Oseltamivir D3


Oseltamivir D3 is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[1].

 Names

Name ethyl (3R,4R,5S)-4-(acetamido-2,2,2-d3)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate

 Oseltamivir D3 Biological Activity

Description Oseltamivir D3 is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[1].
Related Catalog
References

[1]. O Ferraris, et al. Sensitivity of Influenza Viruses to Zanamivir and Oseltamivir: A Study Performed on Viruses Circulating in France Prior to the Introduction of Neuraminidase Inhibitors in Clinical Practice. Antiviral Res. 2005 Oct;68(1):43-8.

 Chemical & Physical Properties

Molecular Formula C16H25D3N2O4
Molecular Weight 315.42300
Exact Mass 315.22400
PSA 90.65000
LogP 2.37660