N,N′-Methylenebisacrylamide

Modify Date: 2025-08-20 09:11:25

N,N′-Methylenebisacrylamide Structure
N,N′-Methylenebisacrylamide structure
Common Name N,N′-Methylenebisacrylamide
CAS Number 110-26-9 Molecular Weight 154.167
Density 1.1±0.1 g/cm3 Boiling Point 445.1±41.0 °C at 760 mmHg
Molecular Formula C7H10N2O2 Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point 215.0±27.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of N,N′-Methylenebisacrylamide


N,N'-Methylenebisacrylamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name N,N'-Methylenebisacrylamide
Synonym More Synonyms

 N,N′-Methylenebisacrylamide Biological Activity

Description N,N'-Methylenebisacrylamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 445.1±41.0 °C at 760 mmHg
Melting Point >300 °C(lit.)
Molecular Formula C7H10N2O2
Molecular Weight 154.167
Flash Point 215.0±27.8 °C
Exact Mass 154.074234
PSA 58.20000
LogP -1.44
Vapour density 5.31 (vs air)
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.475
Storage condition 2-8°C
Water Solubility 0.01-0.1 g/100 mL at 18 ºC

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AS3678000
CHEMICAL NAME :
Acrylamide, N,N'-methylenebis-
CAS REGISTRY NUMBER :
110-26-9
BEILSTEIN REFERENCE NO. :
1706297
LAST UPDATED :
199710
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C7-H10-N2-O2
MOLECULAR WEIGHT :
154.19
WISWESSER LINE NOTATION :
1U1VM1MV1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
390 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - tremor Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>41 ppm/6H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
380 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>41 ppm/6H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>41 ppm/6H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3206 mg/kg/8W-I
TOXIC EFFECTS :
Blood - changes in erythrocyte (RBC) count Blood - changes in leukocyte (WBC) count Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3208 mg/kg
SEX/DURATION :
male 16 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
360 mg/kg
SEX/DURATION :
female 6-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
50 mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
225 mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Dominant lethal test

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
450 mg/kg/5D (Continuous)
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 229,161,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83963 No. of Facilities: 199 (estimated) No. of Industries: 4 No. of Occupations: 5 No. of Employees: 2098 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83963 No. of Facilities: 10 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 66 (estimated) No. of Female Employees: 35 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H332
Personal Protective Equipment Eyeshields;Faceshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes Xn:Harmful
Risk Phrases R20/21/22
Safety Phrases S22-S36/37
RIDADR UN 2811
WGK Germany 2
RTECS AS3678000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2924199090

 Synthetic Route

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N,N′-Methylenebisacrylamide Structure

N,N′-Methyleneb...

CAS#:110-26-9

Literature: Journal of the American Chemical Society, , vol. 75, p. 5027

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N,N′-Methylenebisacrylamide Structure

N,N′-Methyleneb...

CAS#:110-26-9

Literature: Journal of the American Chemical Society, , vol. 75, p. 5027 US2475846 , ;

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N,N′-Methylenebisacrylamide Structure

N,N′-Methyleneb...

CAS#:110-26-9

Literature: US4874822 A1, ;

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N,N′-Methylenebisacrylamide Structure

N,N′-Methyleneb...

CAS#:110-26-9

Literature: Journal of the American Chemical Society, , vol. 73, p. 1028

~%

N,N′-Methylenebisacrylamide Structure

N,N′-Methyleneb...

CAS#:110-26-9

Literature: Journal of the American Chemical Society, , vol. 73, p. 1028

 Preparation

110-26-9 preparation

110-26-9 preparation

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

Methylene bisacrylamide
N,N′-Methylenebisacrylamide
N,N′-methylenediacrylamide
N,N'-Methylenebisacrylamide
N,N‘-Methylenebisacrylamide
N,N-Methylenebisacrylamide
EINECS 203-750-9
N,N'-Methylenediacrylamide
N,N'-Methylenebis(2-propenamide)
MFCD00008625
Bis-acrylamide
N,N'-Methylenebis(acrylamide)
N,N′-methylene-bis-acrylamide
1U1VM1MV1U1
2-Propenamide, N,N'-methylenebis-
N,N'-methanediylbisprop-2-enamide
N-[(prop-2-enoylamino)methyl]prop-2-enamide
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