Phleomycin D1

Modify Date: 2025-08-27 13:07:31

Phleomycin D1 structure	Common Name	Phleomycin D1
	CAS Number	11031-11-1	Molecular Weight	1427.523
	Density	1.8±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₅₅H₈₆N₂₀O₂₁S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Phleomycin D1

Phleomycin D1 (PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. Phleomycin D1 causes cell death by binding and cleaving DNA[1][2][3].

Name	O0VC1NEK5M
Synonym	More Synonyms

Description	Phleomycin D1 (PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. Phleomycin D1 causes cell death by binding and cleaving DNA[1][2][3].
Related Catalog	Research Areas >> Infection
References	[1]. Oliva-Trastoy M, et, al. Resistance to the antibiotic Zeocin by stable expression of the Sh ble gene does not fully suppress Zeocin-induced DNA cleavage in human cells. Mutagenesis. 2005 Mar;20(2):111-4. [2]. Ishizuka M, et, al. Studies on antitumor activity, antimicrobial activity and toxicity of phleomycin. J Antibiot (Tokyo). 1966 Nov;19(6):260-71. [3]. Huang CH, et, al. Bifunctional intercalation of antitumor antibiotics BBM-928A and echinomycin with deoxyribonucleic acid. Effects of intercalation on deoxyribonucleic acid degradative activity of bleomycin and phleomycin. Biochemistry. 1982 Jul 20;21(15):3704-10.

Description

Phleomycin D1 (PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. Phleomycin D1 causes cell death by binding and cleaving DNA[1][2][3].

Related Catalog

Research Areas >> Infection

References

[1]. Oliva-Trastoy M, et, al. Resistance to the antibiotic Zeocin by stable expression of the Sh ble gene does not fully suppress Zeocin-induced DNA cleavage in human cells. Mutagenesis. 2005 Mar;20(2):111-4.

[2]. Ishizuka M, et, al. Studies on antitumor activity, antimicrobial activity and toxicity of phleomycin. J Antibiot (Tokyo). 1966 Nov;19(6):260-71.

[3]. Huang CH, et, al. Bifunctional intercalation of antitumor antibiotics BBM-928A and echinomycin with deoxyribonucleic acid. Effects of intercalation on deoxyribonucleic acid degradative activity of bleomycin and phleomycin. Biochemistry. 1982 Jul 20;21(15):3704-10.

Density	1.8±0.1 g/cm3
Molecular Formula	C₅₅H₈₆N₂₀O₂₁S₂
Molecular Weight	1427.523
Exact Mass	1426.571777
LogP	-4.76
Index of Refraction	1.769
InChIKey	CWCMIVBLVUHDHK-ZSNHEYEWSA-N
SMILES	Cc1c(N)nc(C(CC(N)=O)NCC(N)C(N)=O)nc1C(=O)NC(C(=O)NC(C)C(O)C(C)C(=O)NC(C(=O)NCCC1=NC(c2nc(C(=O)NCCCCN=C(N)N)cs2)CS1)C(C)O)C(OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(OC(N)=O)C1O)c1cnc[nH]1

(2R,3S,4S,5R,6R)-2-{[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[({6-Amino-2-[(1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl]-5-methyl-4-pyrimidinyl}carbonyl)amino]-3-{[(2R,3S,4S)-5-({(2S,3R)-1-[(2-{(4'R)-4-[(4-carbamimidamidobutyl)carbamoyl]-4',5'-dihydro-2,4'-bi-1,3-thiazol-2'-yl}ethyl)amino]-3-hydroxy-1-oxo-2-butanyl}amino)-3-hydroxy-4-methyl-5-oxo-2-pentanyl]amino}-1-(1H-imidazol-4-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)t

O0VC1NEK5M

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Phleomycin D1
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Phleomycin D1
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.