RU-301

Modify Date: 2024-01-18 12:07:41

RU-301 Structure
RU-301 structure
Common Name RU-301
CAS Number 1110873-99-8 Molecular Weight 480.46
Density N/A Boiling Point N/A
Molecular Formula C21H19F3N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RU-301


RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively[1].

 Names

Name RU-301

 RU-301 Biological Activity

Description RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively[1].
Related Catalog
Target

IC50: 10 μM (TAM)[1]

References

[1]. Kimani SG, et al. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7:43908.

 Chemical & Physical Properties

Molecular Formula C21H19F3N4O4S
Molecular Weight 480.46