1110873-99-8

1110873-99-8 structure

Name: RU-301
Chemical Name: RU-301
CAS Number: 1110873-99-8
Molecular Formula: C₂₁H₁₉F₃N₄O₄S
Molecular Weight: 480.46
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK TAM Receptor
Create Date: 2019-10-08 12:53:52
Modify Date: 2024-01-18 12:07:41
RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively[1].

Name	RU-301

Description	RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor
Target	IC50: 10 μM (TAM)[1]
References	[1]. Kimani SG, et al. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7:43908.

Molecular Formula	C₂₁H₁₉F₃N₄O₄S
Molecular Weight	480.46