tert-Butyl (trans-4-hydroxycyclohexyl)carbamate

Modify Date: 2024-01-02 16:02:51

tert-Butyl (trans-4-hydroxycyclohexyl)carbamate Structure
tert-Butyl (trans-4-hydroxycyclohexyl)carbamate structure
Common Name tert-Butyl (trans-4-hydroxycyclohexyl)carbamate
CAS Number 111300-06-2 Molecular Weight 215.289
Density 1.1±0.1 g/cm3 Boiling Point 337.7±31.0 °C at 760 mmHg
Molecular Formula C11H21NO3 Melting Point 172-173ºC
MSDS N/A Flash Point 158.0±24.8 °C

 Names

Name Boc-Trans-4-Aminocyclohexanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 337.7±31.0 °C at 760 mmHg
Melting Point 172-173ºC
Molecular Formula C11H21NO3
Molecular Weight 215.289
Flash Point 158.0±24.8 °C
Exact Mass 215.152145
PSA 58.56000
LogP 1.47
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.485

 Safety Information

Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26
HS Code 2924299090

 Synthetic Route

~99%

tert-Butyl (trans-4-hydroxycyclohexyl)carbamate Structure

tert-Butyl (tra...

CAS#:111300-06-2

Literature: Carter, Percy H.; Cherney, Robert J.; Batt, Douglas G.; Brown, Gregory D.; Duncia, John V.; Gardner, Daniel S.; Yang, Michael G. Patent: US2005/54626 A1, 2005 ; Location in patent: Page/Page column 47 ; US 20050054626 A1

~83%

tert-Butyl (trans-4-hydroxycyclohexyl)carbamate Structure

tert-Butyl (tra...

CAS#:111300-06-2

Literature: Almirall, S.A.; Prat Quinones, Maria; Fonquerna Pou, Silvia; Puig Duran, Carlos; Lumeras Amador, Wenceslao; Aiguade Bosch, Jose; Caturla Javaloyes, Juan Francisco Patent: EP2386555 A1, 2011 ; Location in patent: Paragraph 0073 ;

~92%

tert-Butyl (trans-4-hydroxycyclohexyl)carbamate Structure

tert-Butyl (tra...

CAS#:111300-06-2

Literature: Raju; Anandan, Sampathkumar; Gu, Shihai; Herradura, Prudencio; O'Dowd, Hardwin; Kim, Bum; Gomez, Marcela; Hackbarth, Corinne; Wu, Charlotte; Wang, Wen; Yuan, Zhengyu; White, Richard; Trias, Joaquim; Patel, Dinesh V. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 12 p. 3103 - 3107

~10%

tert-Butyl (trans-4-hydroxycyclohexyl)carbamate Structure

tert-Butyl (tra...

CAS#:111300-06-2

Literature: Synthesis, , # 21 p. 3649 - 3653

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Carbamic acid, N-(cis-4-hydroxycyclohexyl)-, 1,1-dimethylethyl ester
trans-4-(tert-ButoxycarbonylaMino)cyclohexanol
tert-Butyl (trans-4-hydroxycyclohexyl)carbamate
2-Methyl-2-propanyl (cis-4-hydroxycyclohexyl)carbamate
tert-butyl (4-hydroxycyclohexyl)carbamate
MFCD03844613
Carbamic acid, N-(4-hydroxycyclohexyl)-, 1,1-dimethylethyl ester
tert-Butyl (cis-4-hydroxycyclohexyl)carbamate
2-Methyl-2-propanyl (4-hydroxycyclohexyl)carbamate
BOC-TRANS-4-AMINOCYCLOHEXANOL