Satigrel structure
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Common Name | Satigrel | ||
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CAS Number | 111753-73-2 | Molecular Weight | 337.36900 | |
Density | 1.195g/cm3 | Boiling Point | 581.6ºC at 760mmHg | |
Molecular Formula | C20H19NO4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 305.6ºC |
Use of SatigrelSatigrel (E5510) is a potent inhibitor of platelet aggregation. Satigrel inhibits collagen- and arachidonic acid-induced platelet aggregation through preventing thromboxane A2 synthesis by selective inhibition of the target enzyme, PGHS1, which exists in platelets. Satigrel inhibits PGHS1 (IC50: 0.081 μM) and PGHS2 (IC50: 5.9 μM). Satigrel is against Type III PDE, Type V and Type II (IC50: 15.7 μM, 39.8 μM and 62.4 μM, respectively)[1]. |
Name | 4-cyano-5,5-bis(4-methoxyphenyl)pent-4-enoic acid |
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Synonym | More Synonyms |
Description | Satigrel (E5510) is a potent inhibitor of platelet aggregation. Satigrel inhibits collagen- and arachidonic acid-induced platelet aggregation through preventing thromboxane A2 synthesis by selective inhibition of the target enzyme, PGHS1, which exists in platelets. Satigrel inhibits PGHS1 (IC50: 0.081 μM) and PGHS2 (IC50: 5.9 μM). Satigrel is against Type III PDE, Type V and Type II (IC50: 15.7 μM, 39.8 μM and 62.4 μM, respectively)[1]. |
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Related Catalog | |
References |
Density | 1.195g/cm3 |
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Boiling Point | 581.6ºC at 760mmHg |
Molecular Formula | C20H19NO4 |
Molecular Weight | 337.36900 |
Flash Point | 305.6ºC |
Exact Mass | 337.13100 |
PSA | 79.55000 |
LogP | 3.89408 |
Vapour Pressure | 2.27E-14mmHg at 25°C |
Index of Refraction | 1.578 |
E5510 |
5,5-Bis(4-methoxyphenyl)-4-cyano-4-pentenoic acid |
Satigrel |
4-Cyano-5,5-bis(4-methoxyphenyl)-4-pentenoic acid |
4-Pentenoic acid,4-cyano-5,5-bis(4-methoxyphenyl) |
4-Pentenoic acid,5,5-bis(4-methoxyphenyl)-4-cyano |