(1S,3R)-ACPD

Modify Date: 2024-01-09 06:34:29

(1S,3R)-ACPD Structure
(1S,3R)-ACPD structure
Common Name (1S,3R)-ACPD
CAS Number 111900-32-4 Molecular Weight 173.16700
Density 1.452g/cm3 Boiling Point 352.7ºC at 760mmHg
Molecular Formula C7H11NO4 Melting Point N/A
MSDS N/A Flash Point 167.1ºC

 Use of (1S,3R)-ACPD


(1S,3R)-ACPD is a mGluR agonist that can depolarize pyramidal cells[1].

 Names

Name (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid
Synonym More Synonyms

 (1S,3R)-ACPD Biological Activity

Description (1S,3R)-ACPD is a mGluR agonist that can depolarize pyramidal cells[1].
Related Catalog
References

[1]. A E Bandrowski, et al. Metabotropic glutamate receptors modify ionotropic glutamate responses in neocortical pyramidal cells and interneurons. Exp Brain Res. 2001 Jan;136(1):25-40.  

 Chemical & Physical Properties

Density 1.452g/cm3
Boiling Point 352.7ºC at 760mmHg
Molecular Formula C7H11NO4
Molecular Weight 173.16700
Flash Point 167.1ºC
Exact Mass 173.06900
PSA 100.62000
LogP 0.35350
Vapour Pressure 6.39E-06mmHg at 25°C
Index of Refraction 1.563

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY4060000
CHEMICAL NAME :
1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1S-cis)-
CAS REGISTRY NUMBER :
111900-32-4
LAST UPDATED :
199801
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H11-N-O4
MOLECULAR WEIGHT :
173.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases 26-36-36/37

 Synonyms

CB 1712
t-ACPD
1-Aminocyclopentane-1S,3R-dicarboxylic acid
1S,3R-ACPD
1-Amino-1,3-dicarboxycyclopentane
trans-ACPD
MFCD00153760
cis-ACPD
trans-(1S,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid
1-Amino-1,3-cyclopentanedicarboxylic acid