methyl 6-[2-(difluoromethoxy)phenyl]-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate

Modify Date: 2023-01-16 18:38:55

methyl 6-[2-(difluoromethoxy)phenyl]-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate Structure
methyl 6-[2-(difluoromethoxy)phenyl]-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate structure
Common Name methyl 6-[2-(difluoromethoxy)phenyl]-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
CAS Number 111983-60-9 Molecular Weight 326.29500
Density 1.272g/cm3 Boiling Point 470.2ºC at 760 mmHg
Molecular Formula C15H16F2N2O4 Melting Point N/A
MSDS N/A Flash Point 238.2ºC

 Names

Name methyl 6-[2-(difluoromethoxy)phenyl]-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.272g/cm3
Boiling Point 470.2ºC at 760 mmHg
Molecular Formula C15H16F2N2O4
Molecular Weight 326.29500
Flash Point 238.2ºC
Exact Mass 326.10800
PSA 71.36000
LogP 2.00900
Vapour Pressure 5.16E-09mmHg at 25°C
Index of Refraction 1.511

 Synthetic Route

~68%

methyl 6-[2-(difluoromethoxy)phenyl]-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate Structure

methyl 6-[2-(di...

CAS#:111983-60-9

Literature: Kastron, V. V.; Vitolin', R. O.; Kanina, E. L.; Dubur, G. Ya.; Kimenis, A. A. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 8 p. 571 - 574 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 8 p. 948 - 952

 Synonyms

N-Methyl-2-oxo-4-(o-difluoromethoxyphenyl)-5-methoxycarbonyl-6-methyl-1,2,3,4-tetrahydropyrimidine
5-Pyrimidinecarboxylic acid,1,2,3,4-tetrahydro-4-(2-(difluoromethoxy)phenyl)-1,6-dimethyl-2-oxo-,methyl ester
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