R-(-)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide

Modify Date: 2024-01-02 18:50:12

R-(-)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide Structure
R-(-)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide structure
Common Name R-(-)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
CAS Number 112101-81-2 Molecular Weight 244.311
Density 1.2±0.1 g/cm3 Boiling Point 445.5±55.0 °C at 760 mmHg
Molecular Formula C10H15NO4S Melting Point 276-278ºC
MSDS N/A Flash Point 223.2±31.5 °C

 Names

Name R-(-)-5-(2-Amino-propyl)-2-methoxy-benzenesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 445.5±55.0 °C at 760 mmHg
Melting Point 276-278ºC
Molecular Formula C10H15NO4S
Molecular Weight 244.311
Flash Point 223.2±31.5 °C
Exact Mass 244.088165
PSA 98.00000
LogP -0.17
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.557
Storage condition 2-8°C

 MSDS

Name: (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide Material Safety Data Sheet
Synonym:
CAS: 112101-81-2
Section 1 - Chemical Product MSDS Name:(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
112101-81-2 (R)-5-(2-Aminopropyl)-2-methoxybenzene unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 112101-81-2: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white to light yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 168 - 172 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H16N2O3S
Molecular Weight: 244.31

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Not available.
Incompatibilities with Other Materials:
Not available.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 112101-81-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 112101-81-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 112101-81-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 112101-81-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
HS Code 2935009090

 Synthetic Route

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

(R)-(-)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
R-(-)-5-[2(2-Amino-2-Methyl)Ethyl]-2- Methory Benzene Sulfonamide
R-(-)-5-2(2-AMinopropyl)-2-MethoxybenzenesulfonaMide
R-(-)-5-[2(2-AMINO-2-METHYL)ETHYL]-2-METHORY BENZENE SULFONAMIDE
Aminopropyl)-2-methoxybenzene sulfonamide
(2R)-2-amino-1-(4-methoxy-3-sulfamoylphenyl)propane
(R)-1-methyl-2-(3-aminosulfonyl-4-methoxyphenyl)ethylamine
5-[(2R)2-2Aminopropyl]-2-MethoxyBenzeneSulfonamide
5-[(2R)-2-Aminopropyl]-2-methoxybenzenesulfonamide
Benzenesulfonamide, 5-[(2R)-2-aminopropyl]-2-methoxy-
MFCD08704365
5-((2R)-2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE (INTERMEDIATE OF TAMSULOSIN)
R-(-)-5-(2-Amino-propyl)-2-methoxy-benzenesulfonamide
5-[(R)-(2-aminopropyl)]-2-methoxybenzene
(R)-(-)-5-[2(Amino-2-methyl)ethyl]-2-methoxybenzenesulfonamide
R(-)-5-[(2-amino-2-methyl)ethyl]-2-methoxy benzenesulfonamide
R-(-)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
(R)-(-)-5-(2-Aminopropyl)-2-methoxybenzenesulfomide
(R)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide
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