ganodermic acid S

Modify Date: 2024-01-06 08:29:26

ganodermic acid S Structure
ganodermic acid S structure
Common Name ganodermic acid S
CAS Number 112430-63-4 Molecular Weight 554.75700
Density 1.12g/cm3 Boiling Point 633.8ºC at 760mmHg
Molecular Formula C34H50O6 Melting Point N/A
MSDS N/A Flash Point 191.1ºC

 Use of ganodermic acid S


Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic[1].

 Names

Name (E,6R)-6-[(3S,10S,13R,14R,15S,17R)-3,15-diacetyloxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid
Synonym More Synonyms

 ganodermic acid S Biological Activity

Description Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic[1].
Related Catalog
References

[1]. Su CY, et al. Differential effects of ganodermic acid S on the thromboxane A2-signaling pathways in human platelets. Biochem Pharmacol. 1999 Aug 15;58(4):587-95.  

 Chemical & Physical Properties

Density 1.12g/cm3
Boiling Point 633.8ºC at 760mmHg
Molecular Formula C34H50O6
Molecular Weight 554.75700
Flash Point 191.1ºC
Exact Mass 554.36100
PSA 89.90000
LogP 7.43220
Vapour Pressure 1.08E-17mmHg at 25°C
Index of Refraction 1.544

 Synonyms

Lanosta-7,9(11),24-trien-3,15-diacetoxy-26-oic acid
Ganoderic acid R
Ganodermic acid S
Lanosta-7,9(11),24-trien-26-oic acid,3,15-bis(acetyloxy)-,(3beta,15alpha,24E)