MSC 2032964A
Modify Date: 2024-01-09 16:18:09
MSC 2032964A structure
|
Common Name | MSC 2032964A | ||
|---|---|---|---|---|
| CAS Number | 1124381-43-6 | Molecular Weight | 362.309 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 465.2±55.0 °C at 760 mmHg | |
| Molecular Formula | C16H13F3N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 235.1±31.5 °C | |
Use of MSC 2032964AMSC 2032964A is a potent and selective ASK1 inhibitor (IC50 = 93 nM). It blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes and suppresses neuroinflammation in a mouse EAE model. MSC 2032964A is orally bioavailable and brain penetrant. |
| Name | MSC2032964A |
|---|---|
| Synonym | More Synonyms |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 465.2±55.0 °C at 760 mmHg |
| Molecular Formula | C16H13F3N6O |
| Molecular Weight | 362.309 |
| Flash Point | 235.1±31.5 °C |
| Exact Mass | 362.110291 |
| LogP | 1.56 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.706 |
| N-[(2Z)-5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2(3H)-ylidene]nicotinamide |
| 3-Pyridinecarboxamide, N-[(2Z)-5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2(3H)-ylidene]- |
| MSC2032964A |
| MFCD30182335 |