3-Azaspiro[5.5]undecane,hydrochloride (1:1)

Modify Date: 2024-01-12 12:48:24

3-Azaspiro[5.5]undecane,hydrochloride (1:1) structure	Common Name	3-Azaspiro[5.5]undecane,hydrochloride (1:1)
	CAS Number	1125-01-5	Molecular Weight	189.73
	Density	N/A	Boiling Point	273.7ºC at 760 mmHg
	Molecular Formula	C₁₀H₂₀ClN	Melting Point	N/A
	MSDS	N/A	Flash Point	119.3ºC

Use of 3-Azaspiro[5.5]undecane,hydrochloride (1:1)

3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM[1].

Name	3-Azaspiro[5.5]undecane hydrochloride
Synonym	More Synonyms

Description	3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
Target	IC50: 1 μM (influenza A virus M2)[1]
References	[1]. Wang J, et al. Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. ACS Med Chem Lett. 2011 Apr 14;2(4):307-312.

Boiling Point	273.7ºC at 760 mmHg
Molecular Formula	C₁₀H₂₀ClN
Molecular Weight	189.73
Flash Point	119.3ºC
Exact Mass	189.12800
PSA	12.03000
LogP	3.45110
Vapour Pressure	0.00437mmHg at 25°C

Hazard Codes	Xi
HS Code	2933990090

3-Azaspiro[5.5]...

CAS#:180-44-9

~74%

3-Azaspiro[5.5]...

CAS#:1125-01-5

Literature: Wang, Jun; Cady, Sarah D.; Balannik, Victoria; Pinto, Lawrence H.; DeGrado, William F.; Hong, Mei Journal of the American Chemical Society, 2009 , vol. 131, p. 8066 - 8076

3,3-Pentamethyl...

CAS#:1130-32-1

~77%

3-Azaspiro[5.5]...

CAS#:1125-01-5

Literature: DeGrado, William F.; Wang, Jun Patent: US2010/69420 A1, 2010 ; Location in patent: Page/Page column 7 ;

Precursor 2
CAS#:180-44-9 3-Azaspiro[5.5]... CAS#:1130-32-1 3,3-Pentamethyl...
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%