Impurity F of Calcipotriol

Modify Date: 2024-01-04 21:14:37

Impurity F of Calcipotriol Structure
Impurity F of Calcipotriol structure
 Common Name Impurity F of Calcipotriol
CAS Number 112875-61-3 Molecular Weight 641.12600
Density N/A Boiling Point N/A
Molecular Formula C39H68O3Si2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Impurity F of Calcipotriol


Impurity F of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors. IC50 value:Target:Vitamin D3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; Calcipotriol (MC 903; Calcipotriene) exhibits antiproliferative activity against human HL-60, HL60/MX2, MCF-7, T47D, SCC-25 and mouse WEHI-3 cancer cell lines.

 Names

Name (E,1S,4R)-4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-1-cyclopropylpent-2-en-1-ol
Synonym More Synonyms

 Impurity F of Calcipotriol Biological Activity

Description Impurity F of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors. IC50 value:Target:Vitamin D3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; Calcipotriol (MC 903; Calcipotriene) exhibits antiproliferative activity against human HL-60, HL60/MX2, MCF-7, T47D, SCC-25 and mouse WEHI-3 cancer cell lines.
Related Catalog
References

[1]. Binderup (1993) Comparison of calcipotriol with selected metabolites and analogues of vitamin D3: effects on cell growth regulation in vitro and calcium metabolism in vivo. Pharmacol.Toxicol. 72 240.

[2]. Knutson et al (1997) Pharmacokinetics and systemic effect on calcium homeostasis of 1a,24-dihydroxyvitamin D2 in rats. Biochem.Pharmacol. 53 829.

[3]. Wietrzyk et al (2007) Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anticancer Drugs 18 447.111

[4]. Lise Binderup,, Erik Bramm. Effects of a novel vitamin D analogue MC 903 on cell proliferation and differentiation in vitro and on calcium metabolism in vivo. Biochemical Pharmacology. Volume 37, Issue 5, 1 March 1988, Pages 889-895

 Chemical & Physical Properties

Molecular Formula C39H68O3Si2
Molecular Weight 641.12600
Exact Mass 640.47100
PSA 38.69000
LogP 11.14960
Storage condition 2-8℃

 Synthetic Route

 Synonyms

1,3-Bis-O-(tert-butyldimethylsilyl)calcipotriene
(1S,3R)-bis(tert-butyldimethylsilyloxy)-20(R)-(3'(S)-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(Z),7(E),10(19)-triene
1(S),3(R)-bis(tert-butyl-dimethylsilyloxy)-20(R)-(3'-cyclopropyl-3(S)'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(Z),7(E),10(19)-triene
UNII-4SP93VP62P
Impurity F of Calcipotriol
Top Suppliers:I want be here

No recommended suppliers.

Get all suppliers and price by the below link:

Impurity F of Calcipotriol suppliers

Price: $1188/1mg

Reference only. check more Impurity F of Calcipotriol price

Related Compounds: More...
Impurity of Calcipotriol
910133-69-6
Impurity of Doxercalciferol
127516-23-8
Ipratropium Bromide Impurity F (Mixture of Diastereomers)
17812-46-3
RAC 5-ETHYL-5-PHENYL-2-(1-PHENYLPROPYL)DIHYDROPYRIMIDINE-4,6(1H,5H)-DIONE(MIXTURE OF DIASTEREOMERS)
1189504-46-8
Ebastine IMpurity F
1429071-63-5
Carbidopa impurity F
1458640-32-8
Acetamide, N-[3-[(2E)-3-[7-[3-(acetylethylamino)phenyl]-3-cyanopyrazolo[1,5-a]pyrimidin-6-yl]-1-oxo-2-propen-1-yl]phenyl]-N-ethyl
940951-61-1
Bromhexine Impurity F
14860-48-1
Flumazenil Impurity F
78756-33-9
Chemsrc provides Impurity F of Calcipotriol(CAS#:112875-61-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Impurity F of Calcipotriol are included as well.>> amp version: Impurity F of Calcipotriol

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved