Altanserin hydrochloride

Modify Date: 2025-08-29 16:29:19

Altanserin hydrochloride Structure
Altanserin hydrochloride structure
Common Name Altanserin hydrochloride
CAS Number 1135280-78-2 Molecular Weight 447.95
Density N/A Boiling Point N/A
Molecular Formula C22H23ClFN3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Altanserin hydrochloride


Altanserin is a 5-hydroxytryptamine (5-HT2A ) selective radioligand. Altanserin delivers human serotonin. Altanserin can be used to study the biochemical and cellular mechanisms of vulnerability to extracellular 5-HT increase [1].

 Names

Name 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one,hydrochloride
Synonym More Synonyms

 Altanserin hydrochloride Biological Activity

Description Altanserin is a 5-hydroxytryptamine (5-HT2A ) selective radioligand. Altanserin delivers human serotonin. Altanserin can be used to study the biochemical and cellular mechanisms of vulnerability to extracellular 5-HT increase [1].
Related Catalog
References

[1]. Pinborg LH, et al. [18F]altanserin binding to human 5HT2A receptors is unaltered after citalopram and pindolol challenge. J Cereb Blood Flow Metab. 2004 Sep;24(9):1037-45.  

 Chemical & Physical Properties

Molecular Formula C22H23ClFN3O2S
Molecular Weight 447.95
Exact Mass 447.11800
PSA 94.00000
LogP 4.15910
InChIKey JFPPLMAMMZZOEA-UHFFFAOYSA-N
SMILES Cl.O=C(c1ccc(F)cc1)C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1

 Altanserin hydrochlorideBioassay

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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: Tocris HTS for Inhibitors of Aerobactin Synthetase lucA
Source: 23265
External Id: IucA Pilot Assay Tocris Library
Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
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 Synonyms

UNII-XUL9717F5K
altanserin hydrochloride
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