Ac-Lys-Gln-Lys-Leu-Arg-AMC trifluoroacetate salt

Modify Date: 2024-01-17 19:44:24

Ac-Lys-Gln-Lys-Leu-Arg-AMC trifluoroacetate salt Structure
Ac-Lys-Gln-Lys-Leu-Arg-AMC trifluoroacetate salt structure
Common Name Ac-Lys-Gln-Lys-Leu-Arg-AMC trifluoroacetate salt
CAS Number 1135686-31-5 Molecular Weight 871.04
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C41H66N12O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ac-Lys-Gln-Lys-Leu-Arg-AMC trifluoroacetate salt


Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)

 Names

Name N2-Acetyl-L-lysyl-L-glutaminyl-L-lysyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide
Synonym More Synonyms

  Biological Activity

Description Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)
Related Catalog

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C41H66N12O9
Molecular Weight 871.04
Exact Mass 870.507568
LogP -1.13
Index of Refraction 1.631

 Synonyms

L-Argininamide, N2-acetyl-L-lysyl-L-glutaminyl-L-lysyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
N2-Acetyl-L-lysyl-L-glutaminyl-L-lysyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide