BRD7552
Modify Date: 2025-08-25 10:45:30
BRD7552 structure
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Common Name | BRD7552 | ||
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| CAS Number | 1137359-47-7 | Molecular Weight | 711.626 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 757.6±60.0 °C at 760 mmHg | |
| Molecular Formula | C33H33N3O15 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 412.0±32.9 °C | |
Use of BRD7552BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression.Target: PDX1 [1]in vitro: BRD7552 upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases PDX1 mRNA levels by 2- to 4-fold, with a maximal effect at 5 μM and the expression of MAFA. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells. Treatment of PANC-1 cells with BRD7552 causes a dose-dependent increase in insulin mRNA expression. [1] |
| Name | brd7552 |
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| Synonym | More Synonyms |
| Description | BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression.Target: PDX1 [1]in vitro: BRD7552 upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases PDX1 mRNA levels by 2- to 4-fold, with a maximal effect at 5 μM and the expression of MAFA. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells. Treatment of PANC-1 cells with BRD7552 causes a dose-dependent increase in insulin mRNA expression. [1] |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 757.6±60.0 °C at 760 mmHg |
| Molecular Formula | C33H33N3O15 |
| Molecular Weight | 711.626 |
| Flash Point | 412.0±32.9 °C |
| Exact Mass | 711.191162 |
| PSA | 216.90000 |
| LogP | 7.01 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.654 |
| Storage condition | -20℃ |
| RIDADR | NONH for all modes of transport |
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| α-D-Glucopyranoside, methyl, 2,3-bis(1,3-benzodioxol-5-ylcarbamate) 4-[[4-(ethoxycarbonyl)phenyl]carbamate] |
| Methyl 2,3-bis-O-(1,3-benzodioxol-5-ylcarbamoyl)-4-O-{[4-(ethoxycarbonyl)phenyl]carbamoyl}-α-D-glucopyranoside |