IDT307

Modify Date: 2025-08-25 17:05:24

IDT307 Structure
IDT307 structure
Common Name IDT307
CAS Number 1141-41-9 Molecular Weight 340.20300
Density N/A Boiling Point N/A
Molecular Formula C14H17IN2 Melting Point 180-182 °C
MSDS USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of IDT307


IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1].

 Names

Name N,N-dimethyl-4-(1-methylpyridin-1-ium-4-yl)aniline,iodide

 IDT307 Biological Activity

Description IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1].
Related Catalog
In Vitro IDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical (CSF-facing) membrane and sensitive to inhibition by the PMAT inhibitor quinine[1]. IDT307 uptake and intracellular accumulation is greatly attenuated by ~70% in CP tissue from the Pmat knockout mouse[1].
References

[1]. Tao Hu, et al. Molecular mechanisms of organic cation and anion transport at the blood‐CSF barrier. 01 April 2018.

 Chemical & Physical Properties

Melting Point 180-182 °C
Molecular Formula C14H17IN2
Molecular Weight 340.20300
Exact Mass 340.04400
PSA 7.12000
InChIKey CAMWVBRDIKKGII-UHFFFAOYSA-M
SMILES CN(C)c1ccc(-c2cc[n+](C)cc2)cc1.[I-]
Storage condition 20°C

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300
Precautionary Statements P264-P301 + P310
Hazard Codes T
RIDADR UN 2811 6.1 / PGIII

 IDT307Bioassay

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Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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