7-TFA-ap-7-Deaza-ddA

Modify Date: 2025-08-25 22:13:29

7-TFA-ap-7-Deaza-ddA Structure
7-TFA-ap-7-Deaza-ddA structure
Common Name 7-TFA-ap-7-Deaza-ddA
CAS Number 114748-71-9 Molecular Weight 383.325
Density 1.6±0.1 g/cm3 Boiling Point 650.9±55.0 °C at 760 mmHg
Molecular Formula C16H16F3N5O3 Melting Point 167-169 °C(Solv: ethyl ether (60-29-7))
MSDS N/A Flash Point 347.4±31.5 °C

 Use of 7-TFA-ap-7-Deaza-ddA


7-TFA-ap-7-Deaza-ddA (compound 19c, US20060281100A1), a nucleotide derivative, can be used in the synthesis of thiotriphosphate nucleotide dye terminators which can be used in DNA sequencing reactions[1].

 Names

Name 7-TFA-ap-7-Deaza-ddA
Synonym More Synonyms

 7-TFA-ap-7-Deaza-ddA Biological Activity

Description 7-TFA-ap-7-Deaza-ddA (compound 19c, US20060281100A1), a nucleotide derivative, can be used in the synthesis of thiotriphosphate nucleotide dye terminators which can be used in DNA sequencing reactions[1].
Related Catalog
References

[1]. Shen G, et, al. Thiotriphosphate nucleotide dye terminators. US20060281100A1.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 650.9±55.0 °C at 760 mmHg
Melting Point 167-169 °C(Solv: ethyl ether (60-29-7))
Molecular Formula C16H16F3N5O3
Molecular Weight 383.325
Flash Point 347.4±31.5 °C
Exact Mass 383.120514
LogP 1.46
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.639
InChIKey WUXCPWCITSUNMX-WDEREUQCSA-N
SMILES Nc1ncnc2c1c(C#CCNC(=O)C(F)(F)F)cn2C1CCC(CO)O1
Storage condition 2-8℃

 Synonyms

N-(3-{4-Amino-7-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-propyn-1-yl)-2,2,2-trifluoroacetamide
Acetamide, N-[3-[4-amino-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoro-
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