7-Ethoxy-4-(trifluoromethyl)coumarin
7-Ethoxy-4-(trifluoromethyl)coumarin structure
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Common Name | 7-Ethoxy-4-(trifluoromethyl)coumarin | ||
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| CAS Number | 115453-82-2 | Molecular Weight | 258.19300 | |
| Density | 1.368 g/cm3 | Boiling Point | 303.1ºC at 760 mmHg | |
| Molecular Formula | C12H9F3O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 132.7ºC | |
Use of 7-Ethoxy-4-(trifluoromethyl)coumarin7-Ethoxy-4-trifluoromethylcoumarin is a fluorescent substrate of various enzymes of the cytochrome P450 superfamily[1] |
| Name | 7-ethoxy-4-(trifluoromethyl)chromen-2-one |
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| Synonym | More Synonyms |
| Description | 7-Ethoxy-4-trifluoromethylcoumarin is a fluorescent substrate of various enzymes of the cytochrome P450 superfamily[1] |
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| Related Catalog | |
| References |
| Density | 1.368 g/cm3 |
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| Boiling Point | 303.1ºC at 760 mmHg |
| Molecular Formula | C12H9F3O3 |
| Molecular Weight | 258.19300 |
| Flash Point | 132.7ºC |
| Exact Mass | 258.05000 |
| PSA | 39.44000 |
| LogP | 3.21050 |
| Vapour Pressure | 0.000952mmHg at 25°C |
| Index of Refraction | 1.503 |
| InChIKey | OLHOIERZAZMHGK-UHFFFAOYSA-N |
| SMILES | CCOc1ccc2c(C(F)(F)F)cc(=O)oc2c1 |
| Storage condition | 20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi: Irritant; |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2932209090 |
| HS Code | 2932209090 |
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| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics.
Arch. Pharm. Res. 38 , 691-704, (2015) Although various in vitro assays have been developed to evaluate the cytochrome P450 (CYP)-inducing potential of drug candidates, there is a continuing need for the development of a reliable model in ... |
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Environmentally persistent free radical-containing particulate matter competitively inhibits metabolism by cytochrome P450 1A2.
Toxicol. Appl. Pharmacol. 289 , 223-30, (2015) Combustion processes generate different types of particulate matter (PM) that can have deleterious effects on the pulmonary and cardiovascular systems. Environmentally persistent free radicals (EPFRs)... |
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Inhibition of cytochrome P450 2B4 by environmentally persistent free radical-containing particulate matter.
Biochem. Pharmacol. 95 , 126-32, (2015) Combustion processes generate particulate matter (PM) that can affect human health. The presence of redox-active metals and aromatic hydrocarbons in the post-combustion regions results in the formatio... |
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Name: Inhibition of human CYP2B6 assessed as inactivation rate constant at 100 uM for 2 min...
Source: ChEMBL
Target: Cytochrome P450 2B6
External Id: CHEMBL3535630
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Name: Inhibition of rabbit CYP2B4 assessed as inactivation rate constant at 100 uM for 2 mi...
Source: ChEMBL
Target: Cytochrome P450 2B4
External Id: CHEMBL3535631
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Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
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Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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| 2H-1-Benzopyran-2-one,7-ethoxy-4-(trifluoromethyl) |
| 7-Ethoxy-4-(trifluoromethyl)coumarin |
| Ethyl 4-(trifluoromethyl)umbelliferyl ether |
| 7-Ethoxy-4-trifluoromethylcoumarin |
| Etfc cpd |