5-(4-Fluorophenyl)-2-thiophenecarboxylic acid

Modify Date: 2024-04-05 16:26:18

5-(4-Fluorophenyl)-2-thiophenecarboxylic acid Structure
5-(4-Fluorophenyl)-2-thiophenecarboxylic acid structure
Common Name 5-(4-Fluorophenyl)-2-thiophenecarboxylic acid
CAS Number 115933-30-7 Molecular Weight 222.23500
Density 1.38g/cm3 Boiling Point 389.6ºC at 760mmHg
Molecular Formula C11H7FO2S Melting Point 250-254ºC(lit.)
MSDS Chinese USA Flash Point 189.4ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 5-(4-Fluorophenyl)thiophene-2-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.38g/cm3
Boiling Point 389.6ºC at 760mmHg
Melting Point 250-254ºC(lit.)
Molecular Formula C11H7FO2S
Molecular Weight 222.23500
Flash Point 189.4ºC
Exact Mass 222.01500
PSA 65.54000
LogP 3.25240
Vapour Pressure 9.09E-07mmHg at 25°C
Index of Refraction 1.614

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S26
RIDADR NONH for all modes of transport

 Synthetic Route

~99%

5-(4-Fluorophenyl)-2-thiophenecarboxylic acid Structure

5-(4-Fluorophen...

CAS#:115933-30-7

Literature: Fujisawa Pharmaceutical Co., Ltd. Patent: US6770667 B1, 2004 ; Location in patent: Page column 13 ;

~92%

5-(4-Fluorophenyl)-2-thiophenecarboxylic acid Structure

5-(4-Fluorophen...

CAS#:115933-30-7

Literature: Nemoto, Koji; Onozawa, Satoru; Konno, Megumi; Morohashi, Naoya; Hattori, Tetsutaro Bulletin of the Chemical Society of Japan, 2012 , vol. 85, # 3 p. 369 - 371

~%

5-(4-Fluorophenyl)-2-thiophenecarboxylic acid Structure

5-(4-Fluorophen...

CAS#:115933-30-7

Literature: WO2012/59443 A2, ; WO 2012/059443 A2

~%

5-(4-Fluorophenyl)-2-thiophenecarboxylic acid Structure

5-(4-Fluorophen...

CAS#:115933-30-7

Literature: WO2012/59443 A2, ; WO 2012/059443 A2

 Synonyms

5-(4-Fluorophenyl)-2-thiophenecarboxylic acid
5-(4-fluorophenyl)thiophene-2-carboxylic acid
MFCD01316570