Edrophonium chloride
Edrophonium chloride structure
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Common Name | Edrophonium chloride | ||
|---|---|---|---|---|
| CAS Number | 116-38-1 | Molecular Weight | 201.693 | |
| Density | 1.395 g/mL at 25 °C(lit.) | Boiling Point | 130 °C20 mm Hg(lit.) | |
| Molecular Formula | C10H16ClNO | Melting Point | 162-163°C | |
| MSDS | N/A | Flash Point | >230 °F | |
Use of Edrophonium chlorideEdrophonium chloride is a readily reversible acetylcholinesterase inhibitor; prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | edrophonium chloride |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Edrophonium chloride is a readily reversible acetylcholinesterase inhibitor; prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction. |
|---|---|
| Related Catalog |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.395 g/mL at 25 °C(lit.) |
|---|---|
| Boiling Point | 130 °C20 mm Hg(lit.) |
| Melting Point | 162-163°C |
| Molecular Formula | C10H16ClNO |
| Molecular Weight | 201.693 |
| Flash Point | >230 °F |
| Exact Mass | 201.092041 |
| PSA | 20.23000 |
| Index of Refraction | n20/D 1.486(lit.) |
| InChIKey | BXKDSDJJOVIHMX-UHFFFAOYSA-N |
| SMILES | CC[N+](C)(C)c1cccc(O)c1.[Cl-] |
| Storage condition | 2-8°C |
| Water Solubility | reacts |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | BQ5870000 |
| HS Code | 2923900090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~%
Edrophonium chloride CAS#:116-38-1 |
| Literature: DE837098 , ; DRP/DRBP Org.Chem. |
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~%
Edrophonium chloride CAS#:116-38-1 |
| Literature: DE837098 , ; DRP/DRBP Org.Chem. |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 3 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2923900090 |
|---|---|
| Summary | 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Increase the activity of the Burkholderia fixLJ 2-component system
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Burkholderia multivorans
External Id: HMS1625
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01
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Name: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
Source: NCGC
Target: N/A
External Id: SMAD3201
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Name: uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Source: Burnham Center for Chemical Genomics
Target: cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id: SBCCG-A764-CF-PAF-Primary-Assay
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ant...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_ANT_FLUO8_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| edrophonium chloride |
| MFCD00055064 |
| EINECS 204-138-4 |
| Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, chloride (1:1) |
| N-Ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride |
| Ethyl(m-hydroxyphenyl)dimethylammonium chloride |
| Tensilon |
| N-Ethyl-3-hydroxy-N,N-dimethylanilinium chloride |
| ethyl-(3-hydroxyphenyl)-dimethylazanium,chloride |
| Edrophonium (chloride) |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the boiling point of edrophonium chloride? |
| A: Boiling point of edrophonium chloride is 130 °C20 mm Hg(lit.). |
| Q: What is the SMILES notation of edrophonium chloride? |
| A: SMILES notation of edrophonium chloride is CC[N+](C)(C)c1cccc(O)c1.[Cl-]. |
| Q: What are the uses of edrophonium chloride? |
| A: Main uses of edrophonium chloride: Edrophonium chloride is a readily reversible acetylcholinesterase inhibitor; prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction. |
| Q: What are the storage conditions for edrophonium chloride? |
| A: Storage conditions for edrophonium chloride: 2-8°C. |
| Q: What is the melting point of edrophonium chloride? |
| A: Melting point of edrophonium chloride is 162-163°C. |
| Q: What English synonyms does edrophonium chloride have? |
| A: English synonyms of edrophonium chloride: edrophonium chloride, MFCD00055064, EINECS 204-138-4, Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, chloride (1:1), N-Ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride, Ethyl(m-hydroxyphenyl)dimethylammonium chloride, Tensilon, N-Ethyl-3-hydroxy-N,N-dimethylanilinium chloride, ethyl-(3-hydroxyphenyl)-dimethylazanium,chloride, Edrophonium (chloride). |
| Q: What is the InChIKey of edrophonium chloride? |
| A: InChIKey of edrophonium chloride is BXKDSDJJOVIHMX-UHFFFAOYSA-N. |
| Q: What are the upstream materials of edrophonium chloride? |
| A: Related upstream materials(CAS) of edrophonium chloride: 75-03-6;99-07-0;74-96-4. |
| Q: What is the molecular formula of edrophonium chloride? |
| A: Molecular formula of edrophonium chloride is C10H16ClNO. |
| Q: What is the English name of edrophonium chloride? |
| A: The English name of edrophonium chloride is edrophonium chloride. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |