5'-(1,4-dihydro-1-methyl-3-pyridinylcarbonyl)-3'-azido-3'-deoxythymidine
Modify Date: 2025-09-06 21:28:43
5'-(1,4-dihydro-1-methyl-3-pyridinylcarbonyl)-3'-azido-3'-deoxythymidine structure
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Common Name | 5'-(1,4-dihydro-1-methyl-3-pyridinylcarbonyl)-3'-azido-3'-deoxythymidine | ||
|---|---|---|---|---|
| CAS Number | 116333-41-6 | Molecular Weight | 388.37800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H20N6O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
| Name | [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl 1-methyl-4H-pyridine-3-carboxylate |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C17H20N6O5 |
|---|---|
| Molecular Weight | 388.37800 |
| Exact Mass | 388.15000 |
| PSA | 143.64000 |
| LogP | 0.89066 |
| InChIKey | XUUPZVLCORYPPM-BFHYXJOUSA-N |
| SMILES | Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)C3=CN(C)C=CC3)O2)c(=O)[nH]c1=O |
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5'-(1,4-dihydro... CAS#:116333-41-6 |
| Literature: Aggarwal; Gogu; Rangan; Agrawal Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1505 - 1510 |
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~%
5'-(1,4-dihydro... CAS#:116333-41-6 |
| Literature: Aggarwal; Gogu; Rangan; Agrawal Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1505 - 1510 |
|
~%
5'-(1,4-dihydro... CAS#:116333-41-6 |
| Literature: Aggarwal; Gogu; Rangan; Agrawal Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1505 - 1510 |
|
~%
5'-(1,4-dihydro... CAS#:116333-41-6 |
| Literature: Brewster, Marcus E.; Anderson, Wesley R.; Webb, Alistair I.; Pablo, Luisito M.; Meinsma, Donald; Moreno, Dan; Derendorf, Hartmut; Bodor, Nicholas; Pop, Emil Antimicrobial Agents and Chemotherapy, 1997 , vol. 41, # 1 p. 122 - 128 |
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Name: In vitro degradation rate constant in phosphate buffer at pH 7.4
Source: ChEMBL
Target: N/A
External Id: CHEMBL628048
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Name: In vitro time required for 50% hydrolysis at 37 degree Celsius upon incubation in hum...
Source: ChEMBL
Target: N/A
External Id: CHEMBL638460
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Name: In vitro time required for 50% hydrolysis at 37 degree Celsius upon incubation in rat...
Source: ChEMBL
Target: N/A
External Id: CHEMBL638461
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Name: Evaluated in vitro for the concentration required to produce 50% inhibition of replic...
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL693754
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Name: Evaluated in vitro for the concentration required to produce 50% inhibition of prolif...
Source: ChEMBL
Target: H9
External Id: CHEMBL686564
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| DPAZT |
| Zdv-cds |
| H2PyrAZT |
| Azt-cds |
| AZT-DHP |
| HPAZT |